Results 61 to 70 of about 262,063 (287)
VGluT3 BNST neurons transmit GABA and restrict sucrose consumption
Molecular MetabolismObjective: The bed nucleus of the stria terminalis (BNST) is involved in feeding, reward, aversion, and anxiety-like behavior. We identify BNST neurons defined by the expression of vesicular glutamate transporter 3, VGluT3.
Annie Ly +7 more
doaj +1 more source
Cybergeo, 2020 In 2009, the European Commission was mandated by the Parliament to draw up a development strategy for the development of wilderness areas. However, Europe is not known to have vast areas of wilderness or virgin nature, and in this context, considering ...
Alexandra Locquet, Stéphane Héritier
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BMC Public Health, 2023 Background The majority of childhood, Adolescent and Young Adult (AYA) cancer survivors suffers from long-lasting health issues following cancer treatment.
Miek C. Jong +5 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
AN ANALYSIS OF WILLINGNESS TO PARTICIPATE IN WILDERNESS OR OTHER PRIMITIVE AREAS [PDF]
A logit model was used to determine the major factors explaining willingness to participate of an individual in the wilderness or other primitive area visits.
Adhikari, Murali +5 more
core +1 more source
A GIS-based inductive study of wilderness values [PDF]
, 2005 This study presents the results of spatial analysis of wilderness values in Alaska. Using data from two regional planning studies, perceived landscape values from inside and outside wilderness areas were compared to determine if proportionate value ...
Alessa, Lilian, Brown, Gregory
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Ecology and Society, 2003 There are many unique issues associated with natural resource management in the far north as a result of legislative direction, historic settlement and occupation patterns, northern cultural traditions, ecotourism, economic depression, pressures for ...
Alan Watson +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source