Results 61 to 70 of about 34,166 (314)

Measuring MPAs in Continental North America: How Well Protected Are the Ocean Estates of Canada, Mexico, and the USA?

open access: yesFrontiers in Marine Science, 2017
Marine protected areas (MPAs) are a well-established conservation strategy, employed around the world to protect important marine species and ecosystems and support the recovery of declining populations.
Sabine Jessen   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Interrogation autour de la nature et du sauvage à propos de l’établissement de wilderness areas en Europe

open access: yesCybergeo, 2020
In 2009, the European Commission was mandated by the Parliament to draw up a development strategy for the development of wilderness areas. However, Europe is not known to have vast areas of wilderness or virgin nature, and in this context, considering ...
Alexandra Locquet, Stéphane Héritier
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

VGluT3 BNST neurons transmit GABA and restrict sucrose consumption

open access: yesMolecular Metabolism
Objective: The bed nucleus of the stria terminalis (BNST) is involved in feeding, reward, aversion, and anxiety-like behavior. We identify BNST neurons defined by the expression of vesicular glutamate transporter 3, VGluT3.
Annie Ly   +7 more
doaj   +1 more source

A randomized controlled pilot study assessing feasibility and safety of a wilderness program for childhood, adolescent, and young adult cancer survivors: the WAYA study

open access: yesBMC Public Health, 2023
Background The majority of childhood, Adolescent and Young Adult (AYA) cancer survivors suffers from long-lasting health issues following cancer treatment.
Miek C. Jong   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Episode 10 : Wilderness Education : an interview with Connie Saylor

open access: yes, 2011
Interviewee: Connie Saylor | Interviewers: Debbie Lee and Jane Holman | Date: May 6, 2011 | Location: Nezperce, Idaho | Topic: Education in Wilderness | In this episode, titled Wilderness Education, Connie Saylor tells the story of the wilderness that
Debbie Lee; Jane Holman; Connie Saylor;
core  

THE PARADISE IN WILDERNESS: AN EXEGETICAL APPROACH ON MARK 1:9-13 AND ITS SIGNIFICANCE IN CONTEMPORARY SOCIETIES

open access: yesVerbum Christi, 2017
Adam brings humanity from paradise to wilderness by his disobedience toward God. Since then, humanity endures countless sufferings in this world and eternal damnation because of sin.
Jack Kawira
doaj   +1 more source

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