Results 61 to 70 of about 34,166 (314)
Marine protected areas (MPAs) are a well-established conservation strategy, employed around the world to protect important marine species and ecosystems and support the recovery of declining populations.
Sabine Jessen +7 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
In 2009, the European Commission was mandated by the Parliament to draw up a development strategy for the development of wilderness areas. However, Europe is not known to have vast areas of wilderness or virgin nature, and in this context, considering ...
Alexandra Locquet, Stéphane Héritier
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
VGluT3 BNST neurons transmit GABA and restrict sucrose consumption
Objective: The bed nucleus of the stria terminalis (BNST) is involved in feeding, reward, aversion, and anxiety-like behavior. We identify BNST neurons defined by the expression of vesicular glutamate transporter 3, VGluT3.
Annie Ly +7 more
doaj +1 more source
Background The majority of childhood, Adolescent and Young Adult (AYA) cancer survivors suffers from long-lasting health issues following cancer treatment.
Miek C. Jong +5 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Episode 10 : Wilderness Education : an interview with Connie Saylor
Interviewee: Connie Saylor | Interviewers: Debbie Lee and Jane Holman | Date: May 6, 2011 | Location: Nezperce, Idaho | Topic: Education in Wilderness | In this episode, titled Wilderness Education, Connie Saylor tells the story of the wilderness that
Debbie Lee; Jane Holman; Connie Saylor;
core
Adam brings humanity from paradise to wilderness by his disobedience toward God. Since then, humanity endures countless sufferings in this world and eternal damnation because of sin.
Jack Kawira
doaj +1 more source

