Results 111 to 120 of about 29,311 (229)
N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
iNew Medicine, Volume 2, Issue 2, June 2026.ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
Diszregulált miRNS-ek Wilms-tumorban és lehetséges célpontjaik
Bevezetés: A Wilms-tumor a vese malignus daganatos elváltozása, mely leggyakrabban 10 év alatti gyermekek körében fordul elő. Célkitűzés: miRNS-profilozás 10 primer típusú Wilms-tumor szöveti FFPE mintából, valamint 10 kontrollmintából, és az ...
Kabai , Alexandra Barbara
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Wilms Tumor - Pathogenesis, diagnosis, treatment and prognosis
, 2022 Introduction: Wilms tumor is the most common occuring malignant tumor of kidney among children. Mostly appears in infants and young children. The main symptom is enlargement od the abdomen. It is often diagnosed incidentally during USG examination.
Tomasik, Mikołaj +9 more
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Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
Nicholas A. Borja +8 more
wiley +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
MedComm, Volume 7, Issue 6, June 2026.N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
, 2003 The teleost fish are widely used as model organisms in vertebrate biology. The compact genome of the pufferfish, Fugu rubripes, has proven a valuable tool in comparative genome analyses, aiding the annotation of mammalian genomes and the identification ...
Niksic, Martina +5 more
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Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
MedComm – Oncology, Volume 5, Issue 2, June 2026.Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Anaplastic Wilms' tumor: clinical and pathologic studies.
, 1985 A review of almost 1,200 children participating in the first and second National Wilms' Tumor Study (NWTS-1 and -2) has demonstrated a number of significant differences in the clinical presentation and response to therapy of anaplastic and nonanaplastic
B Storer +5 more
core +1 more source
Nutrition in Clinical Practice, Volume 41, Issue 3, Page 768-778, June 2026.Abstract Background Diagnosing malnutrition in patients with pediatric cancer is challenging because tumor masses can interfere with anthropometric measurements. STRONGkids considers cancer a general risk factor, whereas Screening Tool for Childhood Cancer (SCAN) classifies patients as at risk or not, potentially missing those who need nutrition ...
Cristiane Ferreira Marçon +2 more
wiley +1 more source
Bilateral Wilms Tumor - Case Report of a Patient with Family History
Oliwia Rdzanek,1 Patrycja Najda,1 Karolina Parysek-Wójcik,2 Anna Pytlik,2 Monika Lejman,3 Joanna Zawitkowska4 1Student Scientific Society of Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland ...
Pytlik A +5 more
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