Results 91 to 100 of about 25,234 (188)

Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo, Francis S. P. L. Wens, Paulien A. M. A. Raymakers‐Janssen, Lianne M. Haveman, Johannes H. M. Merks, Martine van Grotel, Geert O. Janssens, Marta Fiocco, Marry M. van den Heuvel‐Eibrink, Gerrit van den Berg   +9 more
wiley   +1 more source

Clerodendrum japonicum Extract Suppresses the Pathogenicity of Rheumatoid Arthritis Fibroblast‐Like Synoviocytes by Inhibiting METTL3‐Mediated ICAM2 mRNA Methylation

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Clerodendrum japonicum (Thunb.) Sweet (Clerodendrum japonicum) is a traditional medicinal plant with reported anti‐inflammatory use, but its anti‐rheumatoid arthritis (RA) activity and molecular basis remain insufficiently characterized. Activated fibroblast‐like synoviocytes (FLSs) contribute to persistent inflammation and joint destruction ...
Ying Huang, JiangCun Wei, Yan Ma, XiaoPing Mei, MingTao Huang, Liang Lu, JianLong Zhou, ZuJie Qin   +7 more
wiley   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, Volume 2, Issue 3, September 2026.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Not Too Young to Understand: Meaning Making From the Perspectives of School‐Aged Children With Cancer—A Scoping Review

Psycho-Oncology, Volume 35, Issue 9, September 2026.
ABSTRACT Background Meaning making is increasingly recognized as an important determinant of psychosocial adjustment in adult oncology. However, how school‐aged children make meaning of cancer and how developmental, relational, and sociocultural influences shape this process remain insufficiently characterized, particularly because frameworks are ...
Yixuan Wang, Cheng Jin, Jennifer Currin‐McCulloch, David MacPhee, Abby R. Rosenberg, Yijia Yang, Zhenrong Su, Peichen Liu, Jiameng Wang, Sydney Pryor   +9 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, Volume 104, Issue 6, Page 604-615, September 2026.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, Volume 59, Issue 9, September 2026.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

European Journal of Haematology, Volume 117, Issue 3, Page 682-690, September 2026.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara, Katlyn G. McKay, Harold N. Lovvorn III, Joseph C. Fusco   +3 more
wiley   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

European Journal of Haematology, Volume 117, Issue 3, Page 673-681, September 2026.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source

Brain Metastasis in Wilms' Tumor: a Case Report

Acta Medica Iranica, 2015
Wilms’ tumor is the most common abdominal tumor of childhood, and its cerebral metastasis is apparently very rare. The authors report an 18-month-old girl with Wilms’ tumor and brain metastasis.
Khadijeh Arjmandi, Tahereh Rostami, Saeed Yusefian, Ghasem Miri-Aliabad, Azadeh Kiumarsi, Mitra Mehrazma   +5 more
doaj  

Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor

Genome Medicine
Background Genetic predisposition is particularly common in children with the kidney cancer, Wilms tumor. In 10% of these children, this manifests as a family history of Wilms tumor or bilateral disease.
Jenny Wegert, Silke Appenzeller, Taryn D. Treger, Heike Streitenberger, Barbara Ziegler, Sabrina Bausenwein, Christian Vokuhl, Conor Parks, Eva Jüttner, Susanne Gramlich, Karen Ernestus, Steven W. Warman, Jörg Fuchs, Jochen Hubertus, Dietrich von Schweinitz, Birgit Fröhlich, Norbert Jorch, Ralf Knöfler, Carsten Friedrich, Selim Corbacioglu, Michael C. Frühwald, Arnulf Pekrun, Dominik T. Schneider, Jörg Faber, Jana Stursberg, Markus Metzler, Nils Welter, Kathy Pritchard-Jones, Norbert Graf, Rhoikos Furtwängler, Sam Behjati, Manfred Gessler   +31 more
doaj   +1 more source