Results 11 to 20 of about 25,234 (188)
Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop [PDF]
Advanced Science, EarlyView.In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang +6 more
wiley +2 more sources
Cancer Medicine, 2023 Background Survival after Wilms tumor has significantly increased and focus on late effects has become increasingly important. However, knowledge about long‐term renal function in survivors of Wilms tumor is missing.
Stine Høgsholt +5 more
doaj +1 more source
Clinical Pediatric Hematology-Oncology, 2023 Nephroblastomatosis (NBM) is a precursor of Wilms tumor. We herein report a case in which Wilms tumor was initially suspected and the affected kidney was removed. The tumor was subsequently diagnosed as intralobar NBM and a favorable outcome was achieved
Hirozumi Sano +8 more
doaj +1 more source
Journal of Family Medicine and Primary Care, 2019 Wilms' tumor is most common pediatric renal tumor. Teratoid Wilms' tumor is a variant of Wilms' tumor, in which heterologous tissue predominates. Most commonly, epithelial and mesenchymal tissue present as heterologous component.
Santosh G Rathod +3 more
doaj +1 more source
Asymptomatic adult Wilms' tumor: A case report
Radiology Case Reports, 2022 Background: Wilms' tumor, also called nephroblastoma, is an extremely uncommon kidney tumor of adulthood. We reported a adult man with a left kidney mass diagnosed as Wilms' tumor.Case presentation: A 25-year-old man was hospitalized due to injury of the
Yu-Feng Bai, BSc +8 more
doaj +1 more source
Autoantibody signature differentiates Wilms tumor patients from neuroblastoma patients. [PDF]
PLoS ONE, 2011 Several studies report autoantibody signatures in cancer. The majority of these studies analyzed adult tumors and compared the seroreactivity pattern of tumor patients with the pattern in healthy controls.
Jana Schmitt +11 more
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Teratoid Wilms Tumor: Report of Three Cases and Review of the Literature
Türk Patoloji Dergisi, 2019 Teratoid Wilms tumor is a rare variant of Wilms tumor composed predominantly of well-differentiated epithelial and/or mesenchymal heterologous elements. Like the classical Wilms tumor, this variant may also occur as a renal mass or may be found in extra ...
Doaa AL GHAMDI +2 more
doaj +1 more source
Relapse of Wilms tumor after 20 years: A rare presentation and review of literature
Pediatric Hematology Oncology Journal, 2016 Wilms tumor in children has cure rates of 90% at 5 years with a combined modality of treatment with surgery, chemotherapy and/or radiation. Wilms tumor recurs in 15–20% patients and almost all of them occur within 2 years of diagnosis. Late recurrence in
Venkatraman Radhakrishnan +3 more
doaj +1 more source
Role of expression of p53 and Ki67 in the progression of Wilms tumor: Correlation with patients’ survival [PDF]
Egyptian Journal of Cancer and Biomedical Research, 2021 Background: Wilms tumor (WT) is the most frequent renal tumor of childhood and is a highly responsive tumor to chemotherapy. P53 and ki67 are two of the most important markers that have been evaluated in many cancers.
Ahmad Darwish, Doaa Alemam, Heba Sheta
doaj +1 more source
Surgery for wilms' tumor, Does Preoperative Chemotherapy Ease its Surgical Procedure?
مجلة كلية الطب, 2013 Background: The optimal timing of surgery for Wilms' tumor has been debated for many years. It appears dubious whether surgical ease or per operative complications consistently improved after preoperative chemotherapy. Materials and Methods: This is a
Saad D. Farhan
doaj +1 more source