Results 121 to 130 of about 1,208,988 (206)

Conformational stability and domain‐specific structural features of tumor autoantigens regulate autoantibody epitope propensity

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Autoantibodies against tumor‐associated autoantigens are clinically valuable biomarkers for cancer diagnosis; however, the structural determinants governing epitope selectivity remain unknown. Here, we investigated whether the intrinsic conformational stability of target autoantigens regulates the epitope propensity of tumor‐associated ...
Ai Miyamoto, Rika Yamamoto, Ryui Sakaguchi, Rikako Kutsuma, Takeru Mori, Mirei Masui, Tomoko Honjo, Midori Futami, Mariko Morii, Hiromi Watanabe, Tadahiro Kuribayashi, Kadoaki Ohashi, Katsuyuki Kiura, Junichiro Futami   +13 more
wiley   +1 more source

Brain Metastasis in Wilms' Tumor: a Case Report

Acta Medica Iranica, 2015
Wilms’ tumor is the most common abdominal tumor of childhood, and its cerebral metastasis is apparently very rare. The authors report an 18-month-old girl with Wilms’ tumor and brain metastasis.
Khadijeh Arjmandi, Tahereh Rostami, Saeed Yusefian, Ghasem Miri-Aliabad, Azadeh Kiumarsi, Mitra Mehrazma   +5 more
doaj  

Dynamic Prediction of Clinical Endpoints in Survival Analysis With Machine and Deep Learning: A Systematic Review and Regulatory Perspective

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
ABSTRACT Accurate prediction of time‐to‐event outcomes is essential for clinical decision‐making and model‐informed drug development (MIDD). Conventional survival models may inadequately represent complex longitudinal patient trajectories, time‐dependent treatments, and evolving biomarker or pharmacokinetic/pharmacodynamic (PK/PD) profiles.
Xinyi Liu, Shuai Shao, Dorothee Semiond, Malidi Ahamadi   +3 more
wiley   +1 more source

Tumor de Wilms del adulto [PDF]

, 2015
Se presenta y se comenta un caso de un paciente de 24 años con un tumor de Wilms en el adulto, así como el diagnóstico positivo y diferencial y la terapéutica empleada con mayor frecuencia en esta enfermedad.
Fernández Marichal, Fernando, Pila Pérez, Rafael, Rosales Torres, Pedro, Pila Peláez, Rafael, Vázquez Drake, Charles   +4 more
core  

Foreword

, 2016
I have been lucky and privileged to work with the Société Internationale d’Oncologie Pédiatrique (SIOP) panel of pathologists for 40 years. During this time, I have seen steady and remarkable progress and success in the treatment of Wilms’ tumour, with ...
Sandstedt, B, Bengt Sandstedt
core   +1 more source

Negotiating Reproductive Identity After Cancer: A Qualitative Systematic Review of Female Survivors' Post‐Treatment Fertility Experiences

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Fertility concerns are common among female cancer survivors and are shaped by sociocultural influences that extend beyond biomedical outcomes. Previous systematic reviews have consolidated evidence on fertility‐related distress but have tended to operate within clinical or descriptive frameworks.
Yijun Wang, Margo Louise Turnbull, Jeffry Oktavianus, Xiaoyan I. Wu   +3 more
wiley   +1 more source

Bilateral Wilms' tumor Bilateral Wilms tumoru

, 2000
Six patients with bilateral Wilms' tumor presenting between 1978 and 1999, were analysed retrospectively. These cases occurred among 108 patients of Wilms' tumor giving an incidence of 5.5%.
Buyukunal, C., Danismend, N., Yeker, Y., EROĞLU, Ergün, Yuksel, L., Dervisoglu, S., Soylet, Y., Topuzlu Tekant, Gonca Ayşe, YILDIZ, İbrahim   +8 more
core  

Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor

Genome Medicine
Background Genetic predisposition is particularly common in children with the kidney cancer, Wilms tumor. In 10% of these children, this manifests as a family history of Wilms tumor or bilateral disease.
Jenny Wegert, Silke Appenzeller, Taryn D. Treger, Heike Streitenberger, Barbara Ziegler, Sabrina Bausenwein, Christian Vokuhl, Conor Parks, Eva Jüttner, Susanne Gramlich, Karen Ernestus, Steven W. Warman, Jörg Fuchs, Jochen Hubertus, Dietrich von Schweinitz, Birgit Fröhlich, Norbert Jorch, Ralf Knöfler, Carsten Friedrich, Selim Corbacioglu, Michael C. Frühwald, Arnulf Pekrun, Dominik T. Schneider, Jörg Faber, Jana Stursberg, Markus Metzler, Nils Welter, Kathy Pritchard-Jones, Norbert Graf, Rhoikos Furtwängler, Sam Behjati, Manfred Gessler   +31 more
doaj   +1 more source

An uncommon case of concurrent tumors: Unilateral Wilm's tumor with contralateral retroperitoneal teratoma in a 3-year-old child

Urology Case Reports
Wilms tumor is the most common renal malignancy in children, while retroperitoneal teratomas are rare. Their simultaneous occurrence at distinct sites is exceptionally rare.
Yasar Rashid, Sajid Ali, Rija Khalid, Tariq Latif   +3 more
doaj   +1 more source

A DRACH Observed/Expected Metric Reveals the Evolutionary Landscape of Epitranscriptomic Regulation Across Bilateria

Annals of the New York Academy of Sciences, Volume 1564, Issue 1, October 2026.
Epitranscriptomic marks are highly variable across life stages and tissues, complicating comparisons between species. Using m6A consensus motifs, we developed a genomic indicator reflecting transcript methylability, the DRACH o/e score, that we used to investigate epitranscriptomic features and associated functions across nine bilaterian species.
Natacha Clairet, Jérémy Le Luyer, Hélène Auger, Maximilian Haeussler, Guillaume Rivière   +4 more
wiley   +1 more source