Results 101 to 110 of about 1,208,988 (206)
Background: Wilms’ tumor is the most common malignant renal tumor in the pediatric age group. This tumor is classically managed by multimodal treatment which involves surgery, radiotherapy and chemotherapy.
Kamal Nain Rattan +2 more
doaj
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat +14 more
wiley +1 more source
Bilateral Adult Wilms\u27 Tumor.
Bilateral Wilms\u27 tumors in children are not uncommon but in the adult are quite rare. A two-mutation theory of oncogenesis has been proposed in which a prezygotic gene mutation and a postzygotic mutation lead to the development of Wilms\u27 tumor ...
Harris, Margaret, MD +3 more
core +1 more source
Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega +10 more
wiley +1 more source
Rhabdomyosarcoma mimicking Wilms' tumor
A case of a 6 year old child, with a pleomorphic rhabdomyosarcoma involving simultaneously the leg muscles and the kidney is reported. The renal tumor distorted the pyelocalycial system and Wilms' tumor was the clinical diagnosis.
Mendonça, Núbia [UNESP] +2 more
core +1 more source
Renal Neuroendocrine Tumor Mimicking Upper Tract Urothelial Carcinoma
ABSTRACT Introduction Renal pelvic or peripelvic neuroendocrine tumors are rare and may radiologically mimic invasive upper tract urothelial carcinoma. Case Presentation A man in his 70s presented with two episodes of painless gross hematuria and lower urinary tract symptoms from benign prostatic hyperplasia.
Jia‐Yuh Sheu +2 more
wiley +1 more source
The Clinical Relevance of Age at Presentation in Nephroblastoma
The most important prognostic factors for Wilms tumor (WT) patients seem to be stage, histological subtype, and 1p/16q loss of heterozygosity (LOH) in chemotherapy-naive WTs.
core +1 more source
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić +5 more
wiley +1 more source
CCNE1: A Cell Cycle Regulator That Influences Tumor Progression
ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan +6 more
wiley +1 more source
Diszregulált miRNS-ek Wilms-tumorban és lehetséges célpontjaik
Bevezetés: A Wilms-tumor a vese malignus daganatos elváltozása, mely leggyakrabban 10 év alatti gyermekek körében fordul elő. Célkitűzés: miRNS-profilozás 10 primer típusú Wilms-tumor szöveti FFPE mintából, valamint 10 kontrollmintából, és az ...
Kabai , Alexandra Barbara
core

