Results 81 to 90 of about 1,208,988 (206)

Kidney: Nephroblastoma (Wilms tumor) [PDF]

, 2007
Review on Kidney: Nephroblastoma (Wilms tumor), with data on clinics, and the genes ...
Erson, AE, Petty, EM
core   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Quantitative RT-PCR-based miRNA profiling of blastemal Wilms’ tumors

, 2018
A blastemás Wilms-tumorok kedvezőtlen prognózist mutatnak a kemoterápiára való alacsony érzékenység miatt. Célunk a kísérlet során az volt, hogy hozzájáruljunk a betegség miRNSprofilozásához és megvizsgáljuk, hogy felhasználhatunk-e FFPE mintákat miRNS-
Berki, Zsanett
core  

m6A‐Mediated Stabilization of MRPS23 Drives NSCLC Progression Via HSPA8 and ERK Signaling Modulation

Cancer Science, EarlyView.
MRPS23 mRNA is m6A‐methylated by WTAP and stabilized by IGF2BP3, leading to increased MRPS23 protein. MRPS23 physically interacts with HSPA8, and this interaction is functionally associated with activation of the RAS–RAF–MEK–ERK pathway, ultimately promoting NSCLC cell proliferation and tumor progression.
Sihong Le, Yitao Le, Xianshen Sha, Feng Qiu, Ling Zhang   +4 more
wiley   +1 more source

Mosaic DICER1 RNase IIIb hotspot mutation with multiple tumors: case report and literature review

Frontiers in Oncology
We present a case of a 6-month-old boy who was diagnosed with Peutz–Jeghers polyps, intestine fusiform mesenchymal tumor, Wilms tumor, and Ir type pleuropulmonary blastoma (PPB) successively, with mosaic DICER1 RNase IIIb hotspot mutation: c.5113G>A p.
Peiyi Yang, Mei Jin, Wen Zhao, Chao Duan, Jie Yu, Yanchao Qu, Libing Fu, Tong Yu, Xiaoman Wang, Ruolan Guo, Chunying Cui, Dong Mei, Yan Su   +12 more
doaj   +1 more source

Treatment‐Free Remission in Chronic Myeloid Leukemia: Toward Precision and Personalized Approaches to Functional Cure

Cancer Science, EarlyView.
Immune surveillance of residual leukemic stem cells after tyrosine kinase inhibitor discontinuation involves coordinated NK‐cell, CTL, Treg, pDC, and neutrophil activity that predicts treatment‐free remission, while exhausted CTLs and Treg expansion predict relapse in chronic myeloid leukemia.
Hiroshi Ureshino, Shinya Kimura
wiley   +1 more source

Rare case of primary bladder Wilm's tumor in a 1-year old boy

Urology Case Reports, 2019
Extrarenal Wilms' tumor (EWRT) is a rare entity, but primary bladder Wilm's tumor is even rarer with only 1 case reported. A 1-year old boy came with chronic urinary retention.
Jufriady Ismy, Jufitriani Ismy, Reno Kamarlis, Akhmad Mustafa   +3 more
doaj   +1 more source

Patient‐Derived Organoids and High‐Throughput Drug Screening: Advancing Functional Precision Medicine in Pediatric Cancer

Organ Medicine, EarlyView.
Yiyang Bao, Xingfei Chen, Jingyi Huang, Xiaoyu Lin, Yanlai Tang   +4 more
wiley   +1 more source

A Familial Case of Thauvin–Robinet–Faivre Syndrome (TROFAS), Presenting With Postaxial Polydactyly and Upper Lip Vascular Malformation

Clinical Genetics, EarlyView.
These two siblings carrying the homozygous FIBP c.412‐3_415dupCAGTTTG variant, previously identified in several Turkish families, further delineate the clinical spectrum of TROFAS. Postaxial polydactyly and an upper lip vascular malformation, observed in Patient 2, have not previously been reported in association with this syndrome.
Federica Ruscitti, Xenia Latypova, Faustine Ageorges, Antonio Vitobello, Christophe Philippe, Frédéric Tran Mau Them, Yannis Duffourd, Georges Gelwane, Cherine Benzouid, Yline Capri   +9 more
wiley   +1 more source

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

Cell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang, Wenjie Chen, Jingjing Ke, Hongtu Hu, Zhuan Peng, Yue Qi, Guohua Ding, Jijia Hu   +7 more
wiley   +1 more source