Results 71 to 80 of about 1,208,988 (206)

Astragaloside IV Restores Autophagy and Inhibits Apoptosis for Podocyte Protection in Diabetic Nephropathy by Inhibiting Notch1 Signaling via SIRT6‐Mediated Deacetylation

Phytotherapy Research, EarlyView.
AS‐IV binds to SIRT6 and promotes H3K9 deacetylation at the Notch1 promoter, inhibiting gene transcription (Created with BioGDP.com). ABSTRACT Astragaloside IV (AS‐IV) has demonstrated efficacy in ameliorating proteinuria and attenuating renal tubular damage in preclinical diabetic nephropathy (DN) models.
Qiyu Yue, Chen Yong, Xinran Wang, Yang Shu, Min Yao, Yongfei Yu, Yubai Xue, Rong Deng, Tianlu Chu, Weiwei Tao, Min Zhao, Enchao Zhou   +11 more
wiley   +1 more source

Mogroside V Promotes Brown Adipose Thermogenesis via FTO‐m6A‐LETMD1‐UCP1 Pathway to Combat Obesity

Phytotherapy Research, EarlyView.
Mogroside V (MV) alleviates high‐fat diet‐induced obesity and metabolic dysfunction. Mechanistically, MV suppresses FTO expression, thereby increasing m6A modification of Letmd1 mRNA and enhancing its YTHDC2‐dependent stabilization. Theincreased LETMD1 expression is associated with elevated PGC1α and UCP1 levels, contributing to brown adipocyte ...
Yuan‐hai Sun, Ling‐huan Li, Ya‐qian Feng, Teng‐jiao Zhao, Min‐you Qi, Han‐bing Li   +5 more
wiley   +1 more source

De Poenitentiis Et Poenis Ecclesiasticis

Vorlageform des Erscheinungsvermerks: Coloniæ Augustæ Agrippinensium. Excudebat Balthasar Wilms. - Erscheinungsjahr ermittelt in: GV 1700-1910, Bd.
Riegger, Paul Josef
core   +1 more source

Kidney: Nephroblastoma (Wilms tumor) [PDF]

, 1999
Review on Kidney: Nephroblastoma (Wilms tumor), with data on clinics, and the genes ...
Miozzo, M, M Miozzo
core   +1 more source

Lessons from a patient with cardiac arrest due to massive pulmonary embolism as the initial presentation of Wilms tumor: a case report and literature review

BMC Pediatrics, 2019
Background Finding an abdominal mass or hematuria is the initial step in diagnosing Wilms tumor. As the first manifestation of Wilms tumor, it is exceedingly rare for pulmonary tumor embolism to present with cardiac arrest.
Atsuna Fukuda, Takeshi Isoda, Naoya Sakamoto, Keisuke Nakajima, Tetsuya Ohta   +4 more
doaj   +1 more source

Giant Wilms tumor in a child: Safe radical nephrectomy

Journal of Pediatric Surgery Case Reports, 2020
Wilms tumor is the second most common intraabdominal malignancy, and the most common malignant renal tumor in the pediatric age group, accounting for more than 95% of all renal tumors in children.
Moaied A. Hassan
doaj   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Fetal programming and Wilms tumor [PDF]

, 2019
BACKGROUND: The "fetal programming" hypothesis has been evaluated in many adult diseases including cancer, but not for Wilms tumor. Wilms tumor has been related to high birthweight, but little is known about other growth metrics such as a baby's birth ...
Heck, Julia E, He, Di, Hansen, Johnni, Olsen, Jorn, Janzen, Carla, Federman, Noah, Ritz, Beate   +6 more
core   +1 more source

Treatment-independent miRNA signature in blood of wilms tumor patients

BMC Genomics, 2012
Background Blood-born miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior and after preoperative chemotherapy according to SIOP protocol 2001.
Schmitt Jana, Backes Christina, Nourkami-Tutdibi Nasenien, Leidinger Petra, Deutscher Stephanie, Beier Markus, Gessler Manfred, Graf Norbert, Lenhof Hans-Peter, Keller Andreas, Meese Eckart   +10 more
doaj   +1 more source

m6A‐Related Regulation of Ferroptosis Contributes to Nasal Epithelial Barrier Dysfunction in Allergic Rhinitis

Allergy, EarlyView.
This study uses human nasal epithelial cells and BALB/c mice to evaluate the role and molecular mechanism of ferroptosis in HDM‐induced AR, focusing on ferroptosis‐related responses and nasal epithelial barrier disruption. HDM exposure induces lipid peroxidation‐driven ferroptosis and epithelial barrier disruption.
Zehua Lin, Baoai Han, Qiang Xie, Aikebaier Tuohuti, Weisong Cai, Peng Zhou, Jiahao Meng, Qiuyang Fu, Zuhong He, Xiong Chen   +9 more
wiley   +1 more source