Results 111 to 120 of about 3,009,060 (331)

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Rare case of primary bladder Wilm's tumor in a 1-year old boy

open access: yesUrology Case Reports, 2019
Extrarenal Wilms' tumor (EWRT) is a rare entity, but primary bladder Wilm's tumor is even rarer with only 1 case reported. A 1-year old boy came with chronic urinary retention.
Jufriady Ismy   +3 more
doaj   +1 more source

Giant Wilms tumor in a child: Safe radical nephrectomy

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Wilms tumor is the second most common intraabdominal malignancy, and the most common malignant renal tumor in the pediatric age group, accounting for more than 95% of all renal tumors in children.
Moaied A. Hassan
doaj   +1 more source

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

open access: yesCancer Science, EarlyView.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima   +8 more
wiley   +1 more source

Role of CD56 in Normal Kidney Development and Wilms Tumorigenesis [PDF]

open access: yes, 2017
The cell-surface glycoprotein CD56 has three major isoforms that play important roles in cell adhesion and signaling, which may promote cell proliferation, differentiation, survival, or migration.
Brok, J, Pritchard-Jones, K, Yap, L-W
core  

Renal tumor and trauma: a pitfall for conversative management [PDF]

open access: yes, 2011
PURPOSE: Conservative management has been largely used for renal trauma. Although this approach is safe and highly recommended, it can hide a pre-existing unknown condition, such as tumors or urinary malformations. A high index of suspicion is needed for
Abib, Simone de Campos Vieira   +6 more
core   +2 more sources

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara   +3 more
wiley   +1 more source

Successful management of an infant with hypertensive heart failure associated with Wilms’ tumor: a case report

open access: yesJA Clinical Reports, 2020
Background Wilms’ tumor with hyperreninemia may result in critical cardiovascular decompensation. We report a case of severe hypertensive heart failure followed by tumor resection in a 3-month-old infant with Wilms’ tumor. Case presentation A 3-month-old
Hiroko Miura   +4 more
doaj   +1 more source

Wilms Tumor Treatment Outcomes: Perspectives From a Low-Income Setting

open access: yesJournal of Global Oncology, 2016
Purpose Wilms tumor is the commonest renal malignancy in childhood. Survival in high-income countries is approximately 90%, whereas in low-income countries, it is less than 50%.
F. Njuguna   +11 more
semanticscholar   +1 more source

PAX8‐positive conventional urothelial carcinomas of the urinary bladder and their distinct molecular profiles – A clinicopathologic study of 101 consecutive cases with next‐generation sequencing in 20 cases

open access: yesHistopathology, EarlyView.
PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy