Results 51 to 60 of about 3,009,060 (331)

Rare case of blastemal predominant adult Wilms′ tumor with skeletal metastasis case report and brief review of literature

Indian Journal of Urology, 2012
Wilms′ tumor (nephroblastoma) is extremely rare in adults, skeletal metastasis being still rarer. The clinical course of adult Wilms′ tumor is very aggressive.
Rashmi Patnayak, D. V. S. Rambabu, Amitabh Jena, Bodagala Vijaylaxmi, B V Phaneendra, M Kumaraswamy Reddy   +5 more
doaj   +1 more source

METTL3 regulates WTAP protein homeostasis [PDF]

, 2018
The Wilms tumor 1 (WT1)-associated protein (WTAP) is upregulated in many tumors, including, acute myeloid leukemia (AML), where it plays an oncogenic role by interacting with different proteins involved in RNA processing and cell proliferation.
Capuano, Ernestina, Cruciani, Sonia, Fatica, Alessandro, Fazi, Francesco, Ginistrelli, Lavinia Ceci, Ianniello, Zaira, Larivera, Simone, Marchioni, Marcella, Sorci, Melissa   +8 more
core   +2 more sources

Association of KRAS and NRAS gene polymorphisms with Wilms tumor risk: a four-center case-control study

Aging, 2019
Wilms tumor is a type of pediatric solid tumor that arises partly due to somatic and germline mutations. Single-nucleotide polymorphisms (SNPs) in the RAS gene reportedly modify the risk for several types of human malignancies. We conducted a multicenter
W. Fu, Zhenjian Zhuo, Rui-Xi Hua, Kai Fu, Wei Jia, Jinhong Zhu, Jiao Zhang, Jiwen Cheng, Haixia Zhou, H. Xia, Jing He, Guochang Liu   +11 more
semanticscholar   +1 more source

miR-483-5p Targets MKNK1 to Suppress Wilms’ Tumor Cell Proliferation and Apoptosis In Vitro and In Vivo

Medical Science Monitor, 2019
Background Wilms’ tumor (WT) is the most common type of renal tumor in children and it has high mortality rates. MicroRNAs (miRNAs) are important regulators of cellular differentiation processes that have been discovered to contribute to the development ...
Kai Liu, B-F He, Jiang Xu, Yang Li, Cheng Guo, Qinhui Cai, Shuya Wang   +6 more
semanticscholar   +1 more source

A big Wilms tumor in a 14-months-old boy

Journal of Education, Health and Sport, 2019
Introduction. Wilms tumor (nephroblastoma) is a malignant neoplasm located in a kidney. It is typical for children and it occurs almost exclusively in a childhood. Purpose of work, material and methods. The aim of the study is presentation of symptoms,
Agnieszka Wójtowicz, Robert Ściślak, Karolina Widłak, Joanna Nurzyńska-Flak   +3 more
doaj   +3 more sources

Expression and prognostic value of Wilms' tumor 1 and early growth response 1 proteins in nephroblastoma [PDF]

, 2000
Wilms' tumor is one of the most common solid tumors of children. The protein product of the tumor-suppressor gene, Wilms' tumor 1 (WT-1), binds to the same DNA sequences as the protein product of the early growth response
Ghanem, M.A.I. (Mazen), Heuvel-Eibrink, M.M. (Marry) van den, Hollander, J.C. (Jan) den, Kwast, Th.H. (Theo) van der, Nassef, S.M., Nijman, R.J.M. (Rien), Noordzij, M.A. (Marinus), Oomen, M.H.A. (Monique), Steenbrugge, G.J. (Gert Jan) van, Sudaryo, M.K.   +9 more
core  

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

DNA Methylation Data-Based Classification and Identification of Prognostic Signature of Children With Wilms Tumor

Frontiers in Cell and Developmental Biology, 2021
Background: As an epigenetic alteration, DNA methylation plays an important role in early Wilms tumorigenesis and is possibly used as marker to improve the diagnosis and classification of tumor heterogeneity.Methods: Methylation data, RNA-sequencing (RNA-
Fucai Tang, Zeguang Lu, Hanqi Lei, Hanqi Lei, Yongchang Lai, Zechao Lu, Zhibiao Li, Zhicheng Tang, Jiahao Zhang, Zhaohui He   +9 more
doaj   +1 more source

Wilms\u27 Tumor and Neuroblastom: Results of Therapy [PDF]

, 1973
Wilms\u27 tumor and neuroblastoma are numerically among the most common noncerebral malignant solid tumors in children.
Maurer, Harold M.
core   +1 more source

Outcomes following autologous hematopoietic stem cell transplant for patients with relapsed Wilms' tumor: a CIBMTR retrospective analysis. [PDF]

, 2017
Despite the marked improvement in the overall survival (OS) for patients diagnosed with Wilms' tumor (WT), the outcomes for those who experience relapse have remained disappointing.
Abdel-Azim, H, Abraham, A, Angel Diaz, M, Dandoy, C, Gale, RP, Guilcher, G, Hale, GA, Hayashi, R, Hemmer, MT, Jodele, S, Kasow, KA, Kitko, C, Le-Rademacher, J, MacMillian, ML, Malogolowkin, MH, Mehta, PA, Smith, AR, Thakar, M, Thiel, EL, Wirk, BM, Woolfrey, A   +20 more
core   +2 more sources