Results 61 to 70 of about 29,255 (243)

Nephron-sparing surgery for Wilms tumor [PDF]

, 2023
The algorithm that has been used successfully in the surgical management of unilateral Wilms tumor, radical nephroureterectomy, cannot be used in children who present with synchronous bilateral renal masses.
Andrew J. Murphy, Andrew M. Davidoff
core   +1 more source

ARTERIOGRAPHY OF WILMS’ TUMOR [PDF]

American Journal of Roentgenology, 1971
Abdominal aortography and selective renal arteriography are important techniques in the aggressive management of Wilms’ tumor. Arteriography provides confirmation of neoplasm, clear delineation of tumor extent, tumor response to therapy, tumor recurrence, liver metastasis, or bilaterality of tumor.Ten cases of Wilms’ tumor are reported.A review of the ...
R E, Clark, A A, Moss, A A, De Lorimier, A J, Palubinskas   +3 more
openaire   +2 more sources

High‐Resolution Genomic Characterization of WAGR Spectrum Disorder: Insights From a Novel Cohort and Literature Synthesis, and Validation of Patient‐Reported Data

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT WAGR spectrum disorder (WAGRSD) is an ultra‐rare congenital disorder caused by heterozygous deletion of chromosome 11p13. While classically associated with Wilms tumor, Aniridia, Genitourinary anomalies, and a Range of developmental delays, accurate delineation of the deletion is critical for prognosis because the phenotypic spectrum extends ...
Andrew M. George, Bamelak T. Duki, Zoe S. Katz, Aravind Viswanathan, Suzanne P. MacFarland, Evan R. Hathaway, Caitlin Monahan, John Morris, Kelly L. Trout, Shari M. Krantz, Arupa Ganguly, Jennifer M. Kalish   +11 more
wiley   +1 more source

Wilms’ Tumour – Histology and Differential Diagnosis

, 2016
Wilms’ tumour (WT) is the most common paediatric renal tumour, which can present as a single nodule, as multifocal unilateral lesions or as bilateral tumours. Typically, WT comprises three histological components namely blastemal, epithelial and stromal.

core   +1 more source

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Wilms’ Tumor in a 37 Years Old [PDF]

, 2010
UNLABELLED: Wilms tumor is rare in adults. Though the approach to diagnosis and treatment of adult Wilms tumor (AWT) is closely modeled on recommendations for childhood Wilms tumor, views differ on how aggressive the treatment should be. We report a case
Thevendran, Gowreeson, Farne, Hugo A, Gowreeson Thevendran, Kaisary, Amir V   +3 more
core   +1 more source

Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor

Cell Reports Medicine
Summary: Wilms tumor is the most common pediatric kidney cancer, and diffuse anaplastic Wilms tumor is the most chemoresistant subtype. Here, we explore how Wilms tumor cells evade the chemotherapy actinomycin D, which inhibits ribosomal RNA biogenesis ...
Patricia D.B. Tiburcio, Kenian Chen, Lin Xu, Kenneth S. Chen   +3 more
doaj   +1 more source

METTL14 gene polymorphisms decrease Wilms tumor susceptibility in Chinese children

BMC Cancer, 2021
Background Wilms tumor is a highly heritable malignancy. Aberrant METTL14, a critical component of N6-methyladenosine (m6A) methyltransferase, is involved in carcinogenesis.
Zhenjian Zhuo, Rui-Xi Hua, Huizhu Zhang, Huiran Lin, Wen Fu, Jinhong Zhu, Jiwen Cheng, Jiao Zhang, Suhong Li, Haixia Zhou, Huimin Xia, Guochang Liu, Wei Jia, Jing He   +13 more
doaj   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Heterogeneity of disease classified as stage III in Wilms tumor: a report from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP).

, 2012
PURPOSE: We analyzed whether the prognosis can differ among Wilms tumors (WT) labeled as Stage III according to currently adopted classification systems.
Nantron M, Provenzi M, AIEOP Wilms Tumor Working Group, PESSION, ANDREA, Bianchi M, D'Angelo P, Gandola L, Indolfi P, Di Cataldo A, Piva L, Terenziani M, Marchianò A, Fossati Bellani F, Collini P, Catania S, Spreafico F   +15 more
core   +1 more source