Results 61 to 70 of about 1,220,485 (237)

Synchronous bilateral Wilms tumor: A report from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP).

, 2013
BACKGROUND: The optimal management of bilateral Wilms tumor (BWT) is challenging, and their survival is lower than for unilateral tumors. This report discusses a large series of BWTs treated in Italy in the last 2 decades.
Di Martino M, CECCHETTO, GIOVANNI, Jenkner A, Bianchi M, On behalf of the AIEOP Wilms Tumor Working Group, Serra A, Crocoli A, Pession A, D'Angelo P, BISOGNO, GIANNI, Gandola L, Inserra A, Conte M, Indolfi P, Terenziani M, Collini P, Biasoni D, Spreafico F   +17 more
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Wilms' tumor: An update

Indian Journal of Urology, 2007
Wilms' tumor (WT) is the commonest pediatric renal tumor, predominantly seen in children less than five years of age. The majority of patients present with an abdominal lump and CT scan is the usual imaging modality for determining the extent of disease.
Hemant B Tongaonkar, Sajid S Qureshi, Purna A Kurkure, Mary-Ann A Muckaden, Brijesh Arora, Thyavihalli B Yuvaraja   +5 more
openaire   +3 more sources

Our Six-year Wilms Tumor Results: A Single-center Experience [PDF]

Objective: This study aimed to analyze the demographic, clinical, and pathological data of children diagnosed with Wilms tumor (WT) and operated on at a tertiary healthcare center. Method: Our study is a retrospective, observational analysis of clinical
Fatma Tuğba Güvenç, Zekeriya İlçe, İlkay Tosun, Onur Şahin, Sevim Yener, Funda Tekkeşin   +5 more
core   +1 more source

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

Wilms’ Tumor in a 37 Years Old [PDF]

, 2010
UNLABELLED: Wilms tumor is rare in adults. Though the approach to diagnosis and treatment of adult Wilms tumor (AWT) is closely modeled on recommendations for childhood Wilms tumor, views differ on how aggressive the treatment should be. We report a case
Thevendran, Gowreeson, Farne, Hugo A, Gowreeson Thevendran, Kaisary, Amir V   +3 more
core   +1 more source

Integrative Transcriptomic Profiling of the Wilms Tumor

, 2023
Our study aimed to identify relevant transcriptomic biomarkers for the Wilms tumor, the most common pediatric kidney cancer, independent of the histological type and stage.
Robert Kordič, Maruša Debeljak, Robert Šket, Olga Blatnik, Tine Tesovnik, Simona Lucija Avčin, Janez Jazbec, Klementina Črepinšek, Blaž Vrhovšek, Jerca Blazina, Jernej Kovač, Lidija Kitanovski, Barbara Jenko Bizjan   +12 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Case Report: Autosomal dominant polycystic kidney disease and Wilms’ tumor in infancy and childhood

Frontiers in Pediatrics
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is rare but one of the most common inherited kidney diseases. Normal kidney function is maintained until adulthood in most patients.
Doviltyte Zina, Doviltyte Zina, Kiudeliene Rosita, Kiudeliene Rosita, Zviniene Kristina, Zviniene Kristina, Rutkauskiene Giedre, Rutkauskiene Giedre, Masalskiene Jurate, Masalskiene Jurate   +9 more
doaj   +1 more source

A Pathologic Link between Wilms Tumor Suppressor Gene, WT1, and IFI16

Neoplasia: An International Journal for Oncology Research, 2008
The Wilms tumor gene (WT1) is mutated or deleted in patients with heredofamilial syndromes associated with the development of Wilms tumors, but is infrequently mutated in sporadic Wilms tumors.
Marianne K-H. Kim, Jacqueline M. Mason, Chi-Ming Li, Windy Berkofsky-Fessler, Le Jiang, Divaker Choubey, Paul E. Grundy, Benjamin Tycko, Jonathan D. Licht   +8 more
doaj   +1 more source