Results 81 to 90 of about 1,220,485 (237)

Lessons from a patient with cardiac arrest due to massive pulmonary embolism as the initial presentation of Wilms tumor: a case report and literature review

open access: yesBMC Pediatrics, 2019
Background Finding an abdominal mass or hematuria is the initial step in diagnosing Wilms tumor. As the first manifestation of Wilms tumor, it is exceedingly rare for pulmonary tumor embolism to present with cardiac arrest.
Atsuna Fukuda   +4 more
doaj   +1 more source

Giant Wilms tumor in a child: Safe radical nephrectomy

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Wilms tumor is the second most common intraabdominal malignancy, and the most common malignant renal tumor in the pediatric age group, accounting for more than 95% of all renal tumors in children.
Moaied A. Hassan
doaj   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Fetal programming and Wilms tumor [PDF]

open access: yes, 2019
BACKGROUND: The "fetal programming" hypothesis has been evaluated in many adult diseases including cancer, but not for Wilms tumor. Wilms tumor has been related to high birthweight, but little is known about other growth metrics such as a baby's birth ...
Heck, Julia E   +6 more
core   +1 more source

Treatment-independent miRNA signature in blood of wilms tumor patients

open access: yesBMC Genomics, 2012
Background Blood-born miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior and after preoperative chemotherapy according to SIOP protocol 2001.
Schmitt Jana   +10 more
doaj   +1 more source

m6A‐Mediated Stabilization of MRPS23 Drives NSCLC Progression Via HSPA8 and ERK Signaling Modulation

open access: yesCancer Science, EarlyView.
MRPS23 mRNA is m6A‐methylated by WTAP and stabilized by IGF2BP3, leading to increased MRPS23 protein. MRPS23 physically interacts with HSPA8, and this interaction is functionally associated with activation of the RAS–RAF–MEK–ERK pathway, ultimately promoting NSCLC cell proliferation and tumor progression.
Sihong Le   +4 more
wiley   +1 more source

Kidney: Nephroblastoma (Wilms tumor) [PDF]

open access: yes, 2007
Review on Kidney: Nephroblastoma (Wilms tumor), with data on clinics, and the genes ...
Erson, AE, Petty, EM
core   +1 more source

Treatment‐Free Remission in Chronic Myeloid Leukemia: Toward Precision and Personalized Approaches to Functional Cure

open access: yesCancer Science, EarlyView.
Immune surveillance of residual leukemic stem cells after tyrosine kinase inhibitor discontinuation involves coordinated NK‐cell, CTL, Treg, pDC, and neutrophil activity that predicts treatment‐free remission, while exhausted CTLs and Treg expansion predict relapse in chronic myeloid leukemia.
Hiroshi Ureshino, Shinya Kimura
wiley   +1 more source

Quantitative RT-PCR-based miRNA profiling of blastemal Wilms’ tumors

open access: yes, 2018
A blastemás Wilms-tumorok kedvezőtlen prognózist mutatnak a kemoterápiára való alacsony érzékenység miatt. Célunk a kísérlet során az volt, hogy hozzájáruljunk a betegség miRNSprofilozásához és megvizsgáljuk, hogy felhasználhatunk-e FFPE mintákat miRNS-
Berki, Zsanett
core  

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

open access: yesCell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy