Results 161 to 170 of about 11,342 (257)

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Wilson's Disease Myopathy: A Case Report and Brief Literature Review. [PDF]

Cureus
Riccione NM, Chan CN.
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Case Report: A case of focal segmental glomerulosclerosis in Wilson's disease induced by penicillamine. [PDF]

Front Med (Lausanne)
Li Q, Yang L, Zheng X, Zhang Y.
europepmc   +1 more source

Do Linking‐Expression Substitutions Mitigate Deterministic Interpretations of Genetic Information?

Journal of Applied Philosophy, EarlyView.
ABSTRACT It is a common concern that broader audiences interpret scientific information about the genetic correlates and causes of complex human traits in an overly deterministic manner. A frequently proposed way to address this issue is to carefully select the linking expressions used to describe gene–trait relationships when communicating genetic ...
Riin Kõiv
wiley   +1 more source

Can Parkinsonism be a solitary manifestation of Wilson's Disease? [PDF]

Clin Park Relat Disord
Salari M, Hojjatipour F, Rezaei K, Etemadifar M.   +3 more
europepmc   +1 more source

Legacy and the Politics of Racial Terminology

Journal of Applied Philosophy, EarlyView.
ABSTRACT When a term carries a sordid past, it is tempting to think it should have no future use. Yet the normative life of a word is rarely exhausted by its origins. This article develops legacy analysis as a method for enriching evaluation of what should be done with historically burdened terms. Rather than treating origins as decisive, the framework
Paul‐Mikhail Catapang Podosky
wiley   +1 more source

Evaluation of Ultrasound-Based Parameters for the Assessment of Hepatic Steatosis and Fibrosis in Hungarian Wilson's Disease Patients. [PDF]

Diagnostics (Basel)
Folhoffer A, Zsély B, Krolopp A, Németh D, Tóth T, Lőrinczi C, Hagymási K, Egresi A, Bánhidi C, Halász J, Csongrády B, Budai BK, Stollmayer R, Jakab Z, Laki A, Győri G, Rónaszéki AD, Maurovich-Horvát P, Szalay F, Kaposi PN, Takács I.   +20 more
europepmc   +1 more source

Age‐Associated Variations in Complete Blood Cell Count Parameters and Derived Indices Among Community‐Dwelling Chinese Older Adults

Journal of Clinical Laboratory Analysis, EarlyView.
This cross‐sectional study analyzed data from 9331 participants aged 24–97 to characterize age‐ and sex‐related physiological trajectories of complete blood cell count (CBC) parameters and derived inflammatory indices. Key findings encompassed age‐related declines in red blood cell and platelet counts, elevations in RDW‐CV indices and monocyte ...
Xiangyi Ma, Na Liu, Xiang Wu, Qiudan Chen, Xiaotong Chen, Qingyu Zhou, Shuying Chen, Yong Lin, Xuefeng Wang   +8 more
wiley   +1 more source

Disorders Mimicking Wilson's Disease: Clinical, Biochemical, and Molecular Perspectives for Accurate Differential Diagnosis. [PDF]

Diagnostics (Basel)
Antos A, Gromadzka G, Bembenek JP, Litwin T.   +3 more
europepmc   +1 more source