Results 101 to 110 of about 284,191 (261)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Assessment of Hydrodynamic Performance and Motion Suppression of Tension Leg Floating Platform Based on Tuned Liquid Multi-Column Damper

Journal of Marine Science and Engineering
To address the unstable motion of a tension leg platform (TLP) for floating wind turbines in various sea conditions, an improved method of incorporating a tuned liquid multi-column damper (TLMCD) into the TLP foundation is proposed.
Fuyin Cui, Shuling Chen, Hongbin Hao, Changzhi Han, Ruidong Ni, Yueyue Zhuo   +5 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Design and Testing of a Continuous Conveying and Spreading System for Drying Kelp [PDF]

Progress in Fishery Sciences
Large-scale algal cultivation plays a vital role in the aquaculture industry in China. Saccharina japonica, the predominant species, accounted for 61.4% of the national total algal aquaculture output of 3.0294 million tons in 2024. The harvest window for
JIANG Tao, ZHU Ye, HONG Yang, YANG Meng, TANG Zhenjie   +4 more
doaj   +1 more source

High-entropy ejections from magnetized proto-neutron star winds: implications for heavy element nucleosynthesis

, 2018
Although initially thought to be promising for production of the r-process nuclei, standard models of neutrino-heated winds from proto-neutron stars (PNSs) do not reach the requisite neutron-to-seed ratio for production of the lanthanides and actinides ...
Thompson, Todd A., ud-Doula, Asif
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Dual Loop PI^m PIⁿ Control for an Aileron Positioning

IEEE Access
Aircraft control surfaces are subjected to uncertain design parameters and time–varying external disturbances related to aerodynamic loads. This paper presents a control formulation for their positioning based on a velocity/position dual loop ...
Alessandro De Gaspari, Paolo Mantegazza
doaj   +1 more source

Computation of the modes and polar moment of inertial of the blades of an HAWT [PDF]

, 1981
The coupled differential equations of motion of the blades of a horizontal axis wind turbine are solved numerically, permitting the optimization of the design at relatively low cost.
Beaulieu, G., Noiseux, D.
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Coupling Effect of Waves and Currents on Dynamic Responses of a Semi-Submerged Floating Wind Turbine

Applied Sciences
The effects of wave and current on floating offshore wind turbines (FOWTs) are usually treated separately without considering their inherent interaction.
Bang Wu, Biswajit Basu, Lin Chen, Xugang Hua, Wenxi Wang   +4 more
doaj   +1 more source