Results 171 to 180 of about 3,702,210 (399)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Feasibility Study of using a LiDAR in the complex flowfield of an offshore platform, to measure wind shear profile. [PDF]

, 2011
Offshore wind is the major growth area in the wind industry sector today. However, there remains a key, fundamental missing element - a thorough understanding of the offshore wind climatology and likely wind resource.
Fabre, Sylvie, Scanlon, Thomas, Stickland, Matthew   +2 more
core  

Short‐time wind speed prediction based on Legendre multi‐wavelet neural network [PDF]

, 2023
Xiaoyang Zheng, Dongqing Jia, Zhihan Lv, Chengyou Luo, Junli Zhao, Zeyu Ye   +5 more
openalex   +1 more source

FOEHN WINDS [PDF]

Science, 1899
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

SLOW RADIATION-DRIVEN WIND SOLUTIONS OF A-TYPE SUPERGIANTS [PDF]

, 2011
M. Curé, L. S. Cidale, A. Granada
openalex   +1 more source

Grid Converters for Photovoltaic and Wind Power Systems

, 2011
R. Teodorescu, Marco Liserre, P. Rodríguez   +2 more
semanticscholar   +1 more source

The Wind [PDF]

Proceedings of the Royal Society of Medicine, 1966
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The effects of extreme winds on atmospheric storage tanks

, 2019
Oscar J. Ramírez Olivar, Santiago Zuluaga, Felipe Muñoz, Mauricio Sánchez‐Silva, Jean‐Paul Pinelli, Ernesto Salzano   +5 more
openalex   +2 more sources