Results 101 to 110 of about 8,461,833 (392)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Comparison between upwind and downwind designs of a 10 MW wind turbine rotor [PDF]
Wind Energy Science, 2019 The size of wind turbines has been steadily growing in the pursuit of a lower cost of energy by an increased wind capture. Within this trend, the vast majority of wind turbine rotors have been designed based on the conventional three-bladed upwind ...
P. Bortolotti, A. Kapila, C. L. Bottasso
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Turbulence characterization from a forward-looking nacelle lidar [PDF]
Wind Energy Science, 2017 We present two methods to characterize turbulence in the turbine inflow using radial velocity measurements from nacelle-mounted lidars. The first uses a model of the three-dimensional spectral velocity tensor combined with a model of the spatial ...
A. Peña, J. Mann, N. Dimitrov
doaj +1 more source
Benefits of spatio-temporal modelling for short term wind power forecasting at both individual and aggregated levels [PDF]
, 2017 The share of wind energy in total installed power capacity has grown rapidly in recent years around the world. Producing accurate and reliable forecasts of wind power production, together with a quantification of the uncertainty, is essential to ...
Ackermann +43 more
core +3 more sources
ExaWind: A multifidelity modeling and simulation environment for wind energy
Journal of Physics: Conference Series, 2020 We introduce the open-source ExaWind modeling and simulation environment for wind energy. The primary physics codes of ExaWind are Nalu-Wind and OpenFAST.
M. Sprague +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
An overview of wind-energy-production prediction bias, losses, and uncertainties
Wind Energy Science, 2020 . The financing of a wind farm directly relates to the preconstruction energy yield assessments which estimate the annual energy production for the farm. The accuracy and the precision of the preconstruction energy estimates can dictate the profitability
Joseph C. y. Lee, M. J. Fields
semanticscholar +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Wind Energy in Colombia: A Framework for Market Entry [PDF]
The purpose of this report is to provide decision makers in Colombia (and by extension other countries or regions), who are considering the deployment or consolidation of wind power, with a set of options to promote its use. The options presented are the
Alejandro Deeb +4 more
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