Results 61 to 70 of about 302,569 (311)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Low-power wind energy conversion system with variable structure control for DC grids [PDF]

open access: yes, 2013
This paper presents a discussion on the use of variable structure control, i.e., sliding mode control, for improving the dynamic control performance of a low-power wind energy conversion system (WECS) that is connected to a DC microgrid. The sliding mode
Hui, RSY, Mok, KT, Tan, SC, Yang, Y
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A REVIEW OF CONTROL METHODS OF WIND TURBINE SYSTEMS WITH PERMANENT MAGNET SYNCHRONOUS GENERATOR

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2017
The paper presents a review of control methods of the wind energy conversion systems with permanent magnet synchronous generator. The modern vector control methods for converter system of variable-speed wind energy conversion have been described.
Piotr Gajewski
doaj   +1 more source

Some issues related to power generation using wind energy conversion systems: An overview [PDF]

open access: yes, 2005
Design and successful operation of wind energy conversion systems (WECs) is a very complex task and requires the skills of many interdisciplinary skills, e.g., civil, mechanical, electrical and electronics, geography, aerospace, environmental etc ...
Bansal, R. C.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Utilization of Wind Energy Conversion System in Indonesia [PDF]

open access: yes, 2012
Wind energy is one of the alternative resources that has been developed in Indonesia to support the National Renewable Energy Program. Many areas in Indonesia, have annual wind speed between 2.5 to 5 meter per second.
Saputro, S. M. (Soeripno)
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Edge‐cloud collaborative architecture based multi‐time scales rolling optimization of regional integrated electrical and natural gas energy system considering wind power uncertainty

open access: yesIET Generation, Transmission & Distribution, 2021
With the serious energy crisis and speedy development of natural gas utilization, regional integrated electrical and gas energy system is an efficient way to improve energy potency.
Zhiao Cao   +4 more
doaj   +1 more source

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