Results 41 to 50 of about 102,683 (311)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Analysis of Extreme Wind Pressure Based on Extreme Value Distribution Theory
AtmosphereWhen extreme wind pressure is predicted based on the extreme value distribution theory, the sampling time–distance and sample volume of wind pressure data are important influencing factors. To discuss and analyze the influence of time–distance and sample
Weihu Chen, Yuji Tian, Fan Bai
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Performance of a Vertical Axis Wind Turbine under Accelerating and Decelerating Flows [PDF]
, 2013 Rapid increase in global energy requirements has resulted in considerable attention towards energy generation from the renewable energy sources. In order to meet renewable energy targets, harnessing energy from all available resources including those ...
Paris, Achilleos +3 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Wind loads analysis at the anchorages of the Talavera de la Reina cable stayed bridge [PDF]
, 2014 This paper describes wind tunnel tests performed on wind tunnel models of the Talavera de la Reina cable stayed bridge. The work describes the aeroelastic model construction and it is focused on the evaluation and analysis of the mean and peak wind loads
Squicciarini, G. +9 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Influence of Ultrasonic Wind Sensor Position on Measurement Accuracy under Full-Scale Conditions
Sensors, 2020 A system designed for making field measurements of wind action on engineering structures is described. The system is composed of sonic anemometers, differential pressure sensors, a barometer, and a thermohygrometer.
Tomasz Lipecki +2 more
doaj +1 more source
AIR FLOW AND ENVIRONMENTAL WIND VISUALIZATION USING A CW DIODE PUMPED FREQUENCY DOUBLED Nd:YAG Laser [PDF]
INCAS Bulletin, 2009 Preliminary results obtained in developing a visualisation technique for non-invasive analysis of air flow inside INCAS subsonic wind tunnel and its appendages are presented.
Mircea UDREA +4 more
doaj +1 more source
Determination of wind turbine far wake using actuator disk [PDF]
, 2014 The growth in size of wind turbines over the last years is significant. The rotor diameter becomes somehow comparable to atmospheric boundary layer at the land surface. In this case the assumption of uniform velocity of upcoming wind cannot be valid. The
AMER, Rodeyna +2 more
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