Results 81 to 90 of about 1,027,351 (297)

Determination of the combined vibrational and acoustic emission signature of a wind turbine gearbox and generator shaft in service as a pre-requisite for effective condition monitoring [PDF]

, 2013
This is the post-print version of the final paper published in Renewable Energy. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Bridge, B, Gan, T-H, Van Lieshout, P, Perera, A, Soua, S   +4 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research on Super Capacitor Energy Storage System and Its Control of Wind Power System Based on Virtual Synchronous Technology

Chemical Engineering Transactions, 2016
High penetration of wind power in power grid would seriously affect the frequency safety. Synchronous generator can adjust system power and stabilize grid voltage and grid frequency.
P.F. Xu, K. Shi, H.Q. Zhu, D. Zhao, R.K. Li   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Advanced wind turbine control development using field test analysis for generator overspeed mitigation

Wind Energy
Turbulent and gusty wind conditions can cause generator overspeed peaks to exceed a threshold that then lead to wind turbine shutdowns, which then decrease the energy production of the wind turbines.
Mandar Phadnis, Daniel Zalkind, Lucy Pao
doaj   +1 more source

A Novel Wind Turbine Concept Based on an Electromagnetic Coupler and the Study of Its Fault Ride-through Capability

Energies, 2013
This paper presents a novel type of variable speed wind turbine with a new drive train different from the variable speed wind turbine commonly used nowadays.
Rui You, Braulio Barahona, Jianyun Chai, Nicolaos A. Cutululis   +3 more
doaj   +1 more source

Modeling and Analysis of a Deflection Type Permanent Magnet Synchronous Wind Generator System

Energies, 2020
A novel type of multi-degree-of-freedom (multi-DOF) deflecting-type permanent-magnet synchronous wind generator (PMSWG) is constructed to improve the reliability and utilization of wind energy. The basic working principle of the multi-DOF deflecting-type
Weichao Dong, Zheng Li, Hexu Sun, Jingxuan Zhang   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Intelligent Control for the Variable-Speed Variable-Pitch Wind Energy System

Iranian Journal of Electrical and Electronic Engineering, 2017
In this paper, a new type of multi-variable compensation control method for the wind energy conversion systems (WECS) is presented. Based on wind energy conversion systems, combining artificial neural network (ANN) control and PID, a new type of PID NN ...
M. Heidari
doaj