Results 81 to 90 of about 23,196 (253)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The characteristics of the phenomenon of initiation (sound intonation) in playing the wind instruments

open access: yesArchives of Acoustics, 2015
It was found that the phenomenon of initiation in playing the wind instruments was characterized in particular by the value of the rise time of a sound (ET) and the value of the air flow during its duration.
Zygmunt PAWŁOWSKI, Marek ŻÓŁTOWSKI
doaj  

High-Altitude Wind Field Observation of Airborne Wind Energy System

open access: yes南方能源建设
[Introduction] This work aims to select the optimal wind-measurement instrument to satisfy observational requirements of Airborne Wind Energy System (AWES).
Yanfeng CAI, Xiaoyu LI
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Characterization of aerosol plumes from singing and playing wind instruments associated with the risk of airborne virus transmission. [PDF]

open access: yesIndoor Air, 2022
Wang L   +13 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

A Digital Synthesis Model of Double-Reed Wind Instruments

open access: yesEURASIP Journal on Advances in Signal Processing, 2004
We present a real-time synthesis model for double-reed wind instruments based on a nonlinear physical model. One specificity of double-reed instruments, namely, the presence of a confined air jet in the embouchure, for which a physical model has been ...
Guillemain Ph
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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