Results 31 to 40 of about 1,957,794 (246)

Analysis of Metro Vehicle Operational Stability and Safety under Crosswind Effects

Chengshi guidao jiaotong yanjiu
Objective When urban rail transit trains operate on elevated tracks, crosswinds have a significant impact on the stability and safety of vehicle operation.
Ran LONG, Jinsong ZHOU, Guangyu LIU
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

A Multi-stage Scenario Tree Generation Method for Wind-Solar Load Based on Complex Feature Extraction and Sinkhorn Distance

Zhongguo dianli
The uncertainty in the long-term growth of renewable energy generation output and load has heightened the complexity of power grid planning. Conducting an uncertainty analysis on the long-term scale of renewable energy output and load is of significant ...
Rui WANG, Zhixin FU, Jian WANG, Haoming LIU   +3 more
doaj   +1 more source

Research on Wind Load Calculation Based on Identical Guarantee Rate Method

Shock and Vibration, 2021
Wind load on building surface is one of the main loads for structural design; scholars in this field have put forward some methods to calculate wind load, such as Simiu method and Kasperski method.
Tao Ye, Ledong Zhu, Zhongxu Tan, Lanlan Li   +3 more
doaj   +1 more source

Discussion of Design Wind Loads on a Vaulted Free Roof

Wind, 2022
This paper discusses the wind loads for designing vaulted free roofs based on a wind tunnel experiment, in which the wind force coefficients for the main wind force resisting system and the peak wind force coefficients for cladding are considered.
Wei Ding, Yasushi Uematsu
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Response analysis of large container ship bridge wing structures under dynamic wind loads

Zhongguo Jianchuan Yanjiu
Objectives The aim of this paper is to study the influence of wind load on the safety of the bridge wing structure of a large container ship. MethodsThe variation patterns of dynamic wind load at different vertical positions are investigated and a method
Weipeng ZHOU, Fang SU, JiaLun WANG, Shifeng DING, Qingfeng WANG   +4 more
doaj   +1 more source

Study on wind load characteristics for a container ship under different stacking modes

Zhongguo Jianchuan Yanjiu, 2019
[Objectives]Ship performance evaluation and optimization technology with regard to wind wave factors of real sea area is the key to ship energy efficiency design,and wind load is an important part of the environmental load of wind waves of ships in real ...
Qiao Dan, Ma Ning, Gu Xiechong
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source