Results 51 to 60 of about 531,880 (305)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Improved Frequency Regulation Control Strategy of Wind Power Considering Random Fluctuation Characteristics of Source-Load

发电技术
ObjectivesLarge-scale wind power integration leads to a decrease in grid inertia, and the fluctuating power of wind turbines combined with random fluctuation of load under turbulent wind speed aggravates the frequency fluctuation in the power grid ...
ZHANG Xiaolian, HU Qi, HAO Sipeng, HUANG Peng   +3 more
doaj   +1 more source

Effect of Collaborative Utilization of Energy Storage and Wind Power on Wind Power Grid-connected and Carbon Emission

Chemical Engineering Transactions, 2017
In order to research the effect of collaborative utilization of energy storage and wind power on wind power grid- connected and carbon emission, this paper discussed the correlation between wind power output and load and effect of wind power connected ...
Jia Lu, Renjie Li, Junjie Wang
doaj   +1 more source

Microtab dynamic modelling for wind turbine blade load rejection [PDF]

, 2013
A dynamic model characterising the effect of microtab deployment on the aerodynamics of its base aerofoil is presented. The developed model predicts the transient aerodynamic coefficients consistent with the experimental and computational data reported ...
Alireza Maheri, Ashwill, Baek, Baek, Baker, Bossanyi, Castaignet, Chow, Foley, Frederick, Hayman, Hella, Johnson, Kelkar, Krishna Busawon, Larsen, Larsen, Lobitz, Macquart, Maheri, Terence Macquart, Van Dam, Van Engelen, Wilson, Wilson, Yen   +25 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of Wind Load Exerted on the Jacket Wind Turbines from Optimally Placed Strain Gauges Using C-Optimal Design and Mathematical Model Reduction

Journal of Marine Science and Engineering
Wind turbine towers experience complex dynamic loads during actual operation, and these loads are difficult to accurately predict in advance, which may lead to inaccurate structural fatigue and strength assessment during the structural design phase ...
Fan Zhu, Meng Zhang, Fuxuan Ma, Zhihua Li, Xianqiang Qu   +4 more
doaj   +1 more source

Numerical wind load estimation of offshore floating structures through sustainable maritime atmospheric boundary layer

International Journal of Naval Architecture and Ocean Engineering, 2020
Wind load is one of the major design loads for the hull and mooring of offshore floating structures, especially due to much larger windage area above water than under water.
Seong Mo Yeon, Joo-Sung Kim, Hyun Joe Kim   +2 more
doaj   +1 more source

Wind tunnel test study on the wind load variation law of a point focus solar furnace

Frontiers in Energy Research, 2023
This work studied the wind load acting on a point focus solar furnace composed of a 110 m2 heliostat and a 77 m2 concentrator through wind tunnel testing.
Mingfei He, Mingfei He, Mingfei He, Mingfei He, Penglin Huang, Penglin Huang, Penglin Huang, Penglin Huang, Bo Gong, Bo Gong, Bo Gong, Bo Gong, Chuncheng Zang, Chuncheng Zang, Chuncheng Zang, Chuncheng Zang, Zhifeng Wang, Zhifeng Wang, Zhifeng Wang, Zhifeng Wang   +19 more
doaj   +1 more source

Dynamic load management and optimum sizing of stand-alone hybrid PV/Wind system. [PDF]

, 2015
Simulation algorithms for the sizing of stand-alone hybrid PV/Wind systems are a powerful tool in evaluating the optimum configuration that would cover the energy demand with a predefined reliability level at the lowest cost.
Diamantopoulos, N., Kaplani, Eleni, Ntafogiannis, P., Pappas, K.   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source