Results 61 to 70 of about 531,880 (305)

The analysis of dynamic characteristics and wind-induced displacement response of space Beam String Structure

E3S Web of Conferences, 2018
The Beam String Structure structural system, also called BSS, has the advantages of lighter dead weight and greater flexibility. The wind load is the main design control factor.
Chen Yong Jian, Feng Zhen Fa, Qi Ai, Huang Ying   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Model-based Aeroservoelastic Design and Load Alleviation of Large Wind Turbine Blades

, 2014
This paper presents an aeroservoelastic modeling approach for dynamic load alleviation in large wind turbines with trailing-edge aerodynamic surfaces. The tower, potentially on a moving base, and the rotating blades are modeled using geometrically non ...
Bossanyi E. A., Chattot J.-J., Gaunaa M., Géradin M., Géradin M., Hansen M., Hendriks H. B., Hesse H., Hesse H., Jonkman J., Jonkman J., Jonkman J. M., Larsen T. J., Maciejowski J. M., Passon P., Skogestad S., van Dam C. P., Äström K. J.   +17 more
core   +1 more source

Offshore wind power impact on peak load regulation of power systems [PDF]

, 2014
Peak load regulation in power systems is required to accommodate high levels of power penetration. Wind power generation is a relatively mature technology using renewable energy sources, both on and offshore.
Chen, Qiyu, Littler, Timothy, Wang, Haifeng, Wenling, Jiang   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Performance and Effect of Load Mitigation of a Trailing-Edge Flap in a Large-Scale Offshore Wind Turbine

Journal of Marine Science and Engineering, 2020
As a result of the large-scale trend of offshore wind turbines, wind shear and turbulent wind conditions cause significant fluctuations of the wind turbine’s torque and thrust, which significantly affect the service life of the wind turbine gearbox
Xin Cai, Yazhou Wang, Bofeng Xu, Junheng Feng   +3 more
doaj   +1 more source

Numerical study on active and passive trailing edge morphing applied to a multi-MW wind turbine section [PDF]

, 2015
A progressive increasing in turbine dimension has characterized the technological development in offshore wind energy utilization. This aspect reflects on the growing in blade length and weight.
Boezi, M., Castorrini, Alessio, Corsini, Alessandro, Rispoli, Franco   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Mass-loading of pulsar winds [PDF]

Monthly Notices of the Royal Astronomical Society, 2003
24 pages, 4 ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source