Results 81 to 90 of about 66,305 (312)

Examination of simplified load model on fatigue analysis of small wind turbine blade using aeroelastic analysis

Nihon Kikai Gakkai ronbunshu, 2015
In this research, probabilistic fatigue load estimation by the aeroelastic modeling was carried out for a small wind turbine with 1m diameter. The results were compared with the simplified load model which is a deterministic method, and quantitative ...
Mitsumasa IINO, Hideki TOKUYAMA, Hiroshi SEGAWA, Makoto IIDA   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Influence of Unsteady Wind on the Performance and Aerodynamics of Vertical Axis Wind Turbines [PDF]

, 2012
Interest in small–scale wind turbines as energy sources in the built environment has increased due to the desire of consumers in urban areas to reduce their carbon footprint.
Danao, Louis Angelo
core  

Generation of synthetic benchmark electrical load profiles using publicly available load and weather data

, 2014
Electrical load profiles of a particular region are usually required in order to study the performance of renewable energy technologies and the impact of different operational strategies on the power grid. Load profiles are generally constructed based on
Pillai, Gobind, Putrus, Ghanim, Pearsall, Nicola, Gopalakrishna Pillai, Gobind   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Model simplification and optimization of a passive wind turbine generator [PDF]

, 2009
In this paper, the design of a "low cost full passive structure" of wind turbine system without active electronic part (power and control) is investigated. The efficiency of such device can be obtained only if the design parameters are mutually adapted
B. Sareni, Sareni, Bruno, Abdelli, Abdenour, Roboam, Xavier, A. Abdelli, D.H. Tran, Tran, Duc-Hoan, X. Roboam, Tran, Duc Hoan   +8 more
core   +1 more source

Inverse load calculation procedure for offshore wind turbines and application to a 5-MW wind turbine support structure

, 2022
S.1171-1186A significant number of wind turbines installed today have reached their designed service life of 20 years, and the number will rise continuously.
Pahn, T., Jonkman, J., Rolfes, R.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Optimal Management of a Wind/CAES Power Plant by means of Neural Network Wind Speed Forecast

, 2007
Some of the major limitations of renewable energy sources are represented by their low power density and intermittent nature, largely depending upon local site and unpredictable weather conditions. These problems concur to increase the unit costs of wind
Vincenzo Marano, Gianfranco Rizzo, MARANO, VINCENZO, Ivan Arsie, ARSIE, Ivan, Michael Moran, RIZZO, Gianfranco, Giuseppe Savino   +7 more
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