Results 71 to 80 of about 531,880 (305)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2015 In this research, probabilistic fatigue load estimation by the aeroelastic modeling was carried out for a small wind turbine with 1m diameter. The results were compared with the simplified load model which is a deterministic method, and quantitative ...
Mitsumasa IINO +3 more
doaj +1 more source
Effect of wind turbine generator model and siting on wind power changes out of large WECS arrays [PDF]
, 1981 Methods of reducing the WECS generation change through selection of the wind turbine model for each site, selection of an appropriate siting configuration, and wind array controls are discussed. An analysis of wind generation change from an echelon and a
Dorsey, J. +4 more
core +1 more source
Design and Testing of a Structural Monitoring System in an Almería-Type Tensioned Structure Greenhouse [PDF]
, 2020 Greenhouse cultivation has gained a special importance in recent years and become the basis of the economy in south-eastern Spain. The structures used are light and, due to weather events, often collapse completely or partially, which has generated ...
Marín Membrive, Patricia +2 more
core +1 more source
Structural health monitoring for wind turbine foundations [PDF]
, 2013 The construction of onshore wind turbines has rapidly been increasing as the UK attempts to meet its renewable energy targets. As the UK’s future energy depends more on wind farms, safety and security are critical to the success of this renewable energy ...
Christos Tachtatzis +5 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Economics of Wind Power with Energy Storage [PDF]
We develop a nonlinear mathematical optimization program for investigating the economic and environmental implications of wind penetration in electrical grids and evaluating how hydropower storage could be used to offset wind power intermittence.
G. Cornelis van Kooten +2 more
core
NEW APPROACHES FOR VERY SHORT-TERM STEADY-STATE ANALYSIS OF AN ELECTRICAL DISTRIBUTION SYSTEM WITH WIND FARMS [PDF]
, 2010 Distribution networks are undergoing radical changes due to the high level of penetration of dispersed generation. Dispersed generation systems require particular attention due to their incorporation of uncertain energy sources, such as wind farms, and ...
Angela Russo +9 more
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source