Results 71 to 80 of about 66,305 (312)

Mass-loading of pulsar winds [PDF]

Monthly Notices of the Royal Astronomical Society, 2003
The dynamics of relativistic magnetized mass loaded outflows carrying toroidal magnetic field is analyzed in the context of Pulsar Wind Nebulae (PWNs). Mass loading is very efficient in slowing down super-relativistic magnetized flows and weakening of relativistic shocks.
openaire   +2 more sources

The analysis of dynamic characteristics and wind-induced displacement response of space Beam String Structure

E3S Web of Conferences, 2018
The Beam String Structure structural system, also called BSS, has the advantages of lighter dead weight and greater flexibility. The wind load is the main design control factor.
Chen Yong Jian, Feng Zhen Fa, Qi Ai, Huang Ying   +3 more
doaj   +1 more source

Performance and Effect of Load Mitigation of a Trailing-Edge Flap in a Large-Scale Offshore Wind Turbine

Journal of Marine Science and Engineering, 2020
As a result of the large-scale trend of offshore wind turbines, wind shear and turbulent wind conditions cause significant fluctuations of the wind turbine’s torque and thrust, which significantly affect the service life of the wind turbine gearbox
Xin Cai, Yazhou Wang, Bofeng Xu, Junheng Feng   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Accounting for nonstationarity in the condition monitoring of wind turbine gearboxes [PDF]

, 2013
Increasing growth of wind turbine systems suggests a more systematic research around their design, operation and maintenance is needed. These systems operate under challenging enviromental conditions and failure of some of their parts, for the time being,
Antoniadou, Ifigeneia
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Application of wind generation capacity credits in the Great Britain and Irish systems [PDF]

, 2010
Paper presented at Cigre 2010, 22nd to 27th August 2010, Paris, FranceThe concept of capacity credit is widely used to quantify the contribution of renewable technologies to securing demand.
Hasche, Bernhard, Bialek, J, Hasche, B., Keane, A., Dent, Chris, Bialek, Janusz W., Dent, C.J, Dent, C, Keane, Andrew, Hasche, B, Keane, A, Bialek, J.W.   +11 more
core  

Multi-objective design optimisation of standalone hybrid wind-PV-diesel systems under uncertainties [PDF]

, 2014
Optimal design of a standalone wind-PV-diesel hybrid system is a multi-objective optimisation problem with conflicting objectives of cost and reliability. Uncertainties in renewable resources, demand load and power modelling make deterministic methods of
Maheri, Alireza
core   +1 more source