Results 111 to 120 of about 9,272,003 (312)

Investigating the use of a mesoscale model as part of a feasibility study for a rooftop wind system [PDF]

, 2008
This paper presents the results of a pilot project on rooftop wind in Perth, Western Australia, that aims to gain insight into best practice for placement of rooftop wind systems.
Dreher, H-M, Whale, J., Chand, D.M., Lyons, T.J.   +3 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Analysis of Wind Energy Potential and Optimum Wind Blade Design for Jamshoro Wind Corridor [PDF]

Mehran University Research Journal of Engineering and Technology, 2017
Pakistan is facing energy crisis since last decade. This crisis can be effectively handled by utilizing alternative energy resources. Pakistan has a huge wind energy potential of about 50,000MW. The contribution of costal area of Sindh, Pakistan in the
SYED UMAID ALI, RAFIULLAH KHAN, SYED ATHAR MASOOD   +2 more
doaj  

Wind Characteristics of Three Meteorological Stations in China

Journal of Control Science and Engineering, 2015
With rapid economic development of China, demand for energy is growing rapidly. Many experts have begun to pay attention on exploiting wind energy. Wind characteristics of three meteorological stations in China were analyzed to find out if or not it is ...
Yang Yang, Yao Gang, Wang Rong, Wang Hengyu   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

e-wind: An Integrated Engineering Solution Package for Wind Sensitive Buildings and Structures

, 2011
This article introduces "e-wind" program that is currently under development at Wind Engineering Research Center at Tamkang University. e-wind is an effort to integrate the available wind engineering tools, such as wind code, aerodynamic database and ...
Cheng, Chii-ming; Wang, Jenmu; Chang, Cheng-hsin
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Etude des données du vent et évaluation du potentiel éolien à Nouadhibou (Mauritanie)

Revue des Énergies Renouvelables, 2017
L'objet de cette étude est d'évaluer le potentiel éolien de la région de Nouadhibou. Deux sources de données ont été utilisées. La première concerne les mesures obtenues par la Société Nationale de l’Industrie Minière (SNIM) pendant une durée de 18 mois ...
S.A. Mohamed, A. Beyoud, C.S. Ethmane kane, D. Zejli, M.O Sid Ahmed   +4 more
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source