Results 121 to 130 of about 9,831,735 (311)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

On the Wind Energy in Turkey [PDF]

open access: yes
Increase in negative effects of fossil fuels on the environment has forced many countries, including Turkey, to use renewable energy sources. Today, clean, domestic and renewable energy is commonly accepted as the key for future life, not only for Turkey
Erdogdu, Erkan
core  

Analysis of Wind Energy Potential and Optimum Wind Blade Design for Jamshoro Wind Corridor [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2017
Pakistan is facing energy crisis since last decade. This crisis can be effectively handled by utilizing alternative energy resources. Pakistan has a huge wind energy potential of about 50,000MW. The contribution of costal area of Sindh, Pakistan in the
SYED UMAID ALI   +2 more
doaj  

Wind Characteristics of Three Meteorological Stations in China

open access: yesJournal of Control Science and Engineering, 2015
With rapid economic development of China, demand for energy is growing rapidly. Many experts have begun to pay attention on exploiting wind energy. Wind characteristics of three meteorological stations in China were analyzed to find out if or not it is ...
Yang Yang   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

University Wind Ensemble, November 2, 1975

open access: yes, 2016
Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 2, 1975, program no. 41 of the Department of Music’s 1975-1976 season.University Wind Ensemble, Carl Bjerregaard, conductor ; Stephen ...
Western Michigan University. Wind Ensemble
core  

New National Wind Potential Estimates for Modern and Near-Future Turbine Technologies [PDF]

open access: yes, 2014
Recent advancements in utility-scale wind turbine technology and pricing have vastly increased the potential land area where turbines can be deployed in the United States.
Roberts, J. O.
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Proceedings of the Wind Energy and Birds/Bats Workshop: Understanding and Resolving Bird and Bat Impacts [PDF]

open access: yes, 2004
Most conservation groups support the development of wind energy in the US as an alternative to fossil and nuclear-fueled power plants to meet growing demand for electrical energy.
Schwartz, Susan Savitt
core  

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