Results 141 to 150 of about 9,831,735 (311)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

On the impact of the interval between buildings with urban vertical farms in elliptical plan layouts to wind energy harvesting: a case study

Discover Civil Engineering
Wind energy, as an important sustainable renewable resource, offers significant potential for addressing the energy challenges associated with rapid urbanisation and the excessive reliance on fossil fuels.
Simeng Xie, Pedro Martinez-Vazquez, Charalampos Baniotopoulos   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Wind Power Development: Opportunities and Challenges [PDF]

In this study, the prospects of wind power at the global level are reviewed. Existing studies indicate that the earth’s wind energy supply potential significantly exceeds global energy demand.
Govinda R. Timilsina, G. Cornelis van Kooten   +1 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Turbulence Length Scales in a Boundary Layer Wind Tunnel

, 2001
Turbulence length scales are important parameters affecting the aerodynamic characteristics and response of structures in wind flow. It is therefore essential to simulate the wind velocity profile models in scaling these turbulence length scale ...
Cheung, John C. K., Melbourne, William H.   +1 more
core  

Wind Energy Assessment using a Wind Turbine with Dynamic Yaw Control [PDF]

, 2013
The goal of this project was to analyze the wind energy potential over Lake Michigan. For this purpose, a dynamic model of a utility-scale wind turbine was developed to estimate the potential electrical energy that could be generated.
Pervez, Md Nahid
core  

GEOINFORMATIONAL SUPPORT OF WIND POWER DEVELOPMENT AT THE LOCAL LEVEL

Problemi Bezperervnoï Geografìčnoï Osvìti ì Kartografìï, 2014
The paper deals with the methodology of the potential wind energy generation forecasting for local areas. The results of its application in the Kharkiv region are analyzed.
О.О. Volkovaia, О.S. Tretyakov
doaj  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The effect of variations in soil stiffness on the dynamic response of an offshore wind turbine [PDF]

, 2015
European Wind Energy Agency Offshore Conference, Messe Frankfurt, Germany, 19 - 21 November, 2013Offshore wind is a growing energy sector that has potential to provide vast quantities of the energy required to meet renewable energy targets.
Doherty, Paul, Gavin, Kenneth, Prendergast, Luke J.   +2 more
core