Results 31 to 40 of about 34,253 (219)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Current Status and Prospective of Offshore Wind Power to Achieve Korean Renewable Energy 3020 Plan
대한환경공학회지, 2021 This review comprehensively reviewed floating offshore wind power generation technology, which is being newly developed as a mid- to long-term plan for wind energy.
Minkyu Park +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Development of the Wind Generation Sector and Its Effect on the Grid Operation—The Case of Poland
Energies, 2023 One of the main factors for changes in the structure of the energy mix in Poland is the development of renewable energy sources, in particular wind generation.
Sylwester Robak +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Communications EngineeringThe degradation of electrical insulation is mainly attributed to local defects. Although incorporating organic small molecules into dielectric polymers promotes the insulation strength, accurate suppression of defect development is a long-term and ...
Ke Li +6 more
doaj +1 more source
发电技术, 2019 Several problems at the power characteristics of wind turbine site test such as low efficiency, harsh conditions and unfaithful results are becoming focus in the industry.
Haidi CHAI, Xiaoyan ZHAO, Bo SHI
doaj +1 more source
Applied Computational Intelligence and Soft Computing, 2022 This paper presents the development of a wind power forecasting model based on gene expression programming (GEP) for one of the major wind farms in Sri Lanka, Pawan Danavi.
Damayanthi Herath +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source