Results 41 to 50 of about 34,253 (219)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Anomaly Identification of Wind Turbine Yaw System Based on Two-Stage Attention–Informer Algorithm

Applied Sciences
In response to the problems that abnormal yaw position causes during the yawing process—on the one hand leading to the accumulation of yaw position errors, affecting the accuracy of yawing to the wind or safety due to excessive cable twisting, and on the
Xu Shen, Haiyun Wang, Xiaofang Huang, Yang Chen   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Analysis of China’s Regional Wind Power Generation Efficiency and its Influencing Factors

Chemical Engineering Transactions, 2018
In order to objectively evaluate the current situation of wind power generation in China and identify the key factors, based on the data of 30 Chinese provinces from 2011 to 2014, this study use a meta-frontier data envelopment analysis (DEA) model and a
Xiongfeng Pan, Jing Zhang, Changyu Li, Xianyou Pan   +3 more
doaj   +1 more source

Difference between grid connections of large-scale wind power and conventional synchronous generation

Global Energy Interconnection, 2020
In China, regions with abundant wind energy resources are generally located at the end of power grids. The power grid architecture in these regions is typically not sufficiently strong, and the energy structure is relatively simple.
Jie Li, Chao Liu, Pengfei Zhang, Yafeng Wang, Jun Rong   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Significant Suppression of High Electric Field Regions in XLPE via Voltage Stabilisers

High Voltage
Dielectric degradation typically originates from local defects. The resulting electric field concentration accelerates defect growth. Suppressing field distortion arising from such local weaknesses has long been a major challenge in electrical insulation.
Ke Li, Luming Zhou, Guimin Jiang, Yunxiao Zhang, Yuanxiang Zhou   +4 more
doaj   +1 more source

Effect of Multiple Models of Closed-Loop Transfer Functions on Inter-Harmonic Oscillation Characteristics of Grid-Connected PMSG

CSEE Journal of Power and Energy Systems
Establishing a suitable closed-loop transfer function model for the grid-connected PMSG system is the key basis in performing inter-harmonic characteristics analysis. Multiple closed-loop transfer functions can be constructed when different components of
Jingyi Li, Jianjun Yang, Xiaorong Xie, Haozhi Li, Ke Wang, Zhaohui Shi   +5 more
doaj   +1 more source

How Does Large-scale Wind Power Generation Affect Energy and Reserve Prices? [PDF]

Journal of Operation and Automation in Power Engineering, 2018
Intermittent nature of wind power faced ISO and power producers with new challenges. Wind power uncertainty has increased the required reserve capacity and deployment reserve.
S. M. Zabetian-Hosseini, M. Oloomi Buygi
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source