Results 61 to 70 of about 635,385 (303)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Anomaly Identification of Wind Turbine Yaw System Based on Two-Stage Attention–Informer Algorithm

Applied Sciences
In response to the problems that abnormal yaw position causes during the yawing process—on the one hand leading to the accumulation of yaw position errors, affecting the accuracy of yawing to the wind or safety due to excessive cable twisting, and on the
Xu Shen, Haiyun Wang, Xiaofang Huang, Yang Chen   +3 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Analysis of China’s Regional Wind Power Generation Efficiency and its Influencing Factors

Chemical Engineering Transactions, 2018
In order to objectively evaluate the current situation of wind power generation in China and identify the key factors, based on the data of 30 Chinese provinces from 2011 to 2014, this study use a meta-frontier data envelopment analysis (DEA) model and a
Xiongfeng Pan, Jing Zhang, Changyu Li, Xianyou Pan   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Significant Suppression of High Electric Field Regions in XLPE via Voltage Stabilisers

High Voltage
Dielectric degradation typically originates from local defects. The resulting electric field concentration accelerates defect growth. Suppressing field distortion arising from such local weaknesses has long been a major challenge in electrical insulation.
Ke Li, Luming Zhou, Guimin Jiang, Yunxiao Zhang, Yuanxiang Zhou   +4 more
doaj   +1 more source

Effect of Multiple Models of Closed-Loop Transfer Functions on Inter-Harmonic Oscillation Characteristics of Grid-Connected PMSG

CSEE Journal of Power and Energy Systems
Establishing a suitable closed-loop transfer function model for the grid-connected PMSG system is the key basis in performing inter-harmonic characteristics analysis. Multiple closed-loop transfer functions can be constructed when different components of
Jingyi Li, Jianjun Yang, Xiaorong Xie, Haozhi Li, Ke Wang, Zhaohui Shi   +5 more
doaj   +1 more source

How Does Large-scale Wind Power Generation Affect Energy and Reserve Prices? [PDF]

Journal of Operation and Automation in Power Engineering, 2018
Intermittent nature of wind power faced ISO and power producers with new challenges. Wind power uncertainty has increased the required reserve capacity and deployment reserve.
S. M. Zabetian-Hosseini, M. Oloomi Buygi
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Difference between grid connections of large-scale wind power and conventional synchronous generation

Global Energy Interconnection, 2020
In China, regions with abundant wind energy resources are generally located at the end of power grids. The power grid architecture in these regions is typically not sufficiently strong, and the energy structure is relatively simple.
Jie Li, Chao Liu, Pengfei Zhang, Yafeng Wang, Jun Rong   +4 more
doaj   +1 more source