Results 81 to 90 of about 1,160,501 (293)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Wind Field Retrieval from Satellite Radar Systems [PDF]

, 2002
[eng] Wind observations are essential for determining the atmospheric flow. In particular, sea-surface wind observations are very useful for many meteorological and oceanographic applications.
Portabella Arnús, Marcos
core   +4 more sources

NESZ effects on wind retrievals from Gaofen-3 SAR wave mode data

Frontiers in Earth Science
This study analyzes the effects of noise equivalent sigma zero (NESZ) on wind retrieval accuracy based on the estimated NESZ and wind retrievals from Gaofen-3 (GF3) synthetic aperture radar (SAR) wave mode data. The NESZ was estimated from the normalized
Lin Ren, Lin Ren, Lin Ren, Jinyuan Dai, Jingsong Yang, Jingsong Yang, Chong Jiang, Chong Jiang, Gang Zheng, Gang Zheng, Peng Chen, Xiaohui Li   +11 more
doaj   +1 more source

A Modeling Study of the Impact of the Sea Surface Temperature on the Backscattering Coefficient and Wind Field Retrieval

IEEE Access, 2020
The sea surface temperature (SST) actively impacts the backscattering coefficient measured by scatterometers and the wind retrieval accuracy. However, none of the geophysical model functions (GMFs) currently used in operational wind retrieval considers ...
Yihuan Peng, Xuetong Xie, Mingsen Lin, Cuihong Pan, Haitao Li   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Ocean Vector Wind Retrievals From TRMM Using a Novel Combined Active/Passive Algorithm

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
This article presents a novel ocean vector wind (OVW) retrieval algorithm for remote sensing of ocean winds, using the precipitation radar (PR) and tropical rainfall measurement mission (TRMM) microwave imager (TMI) that operated for >17 years on the ...
Alamgir Hossan, Maria Marta Jacob, W. Linwood Jones   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

ESA´s Wind Lidar Mission ADM-Aeolus: On-Going Scientific Activities Related to Calibration, Retrieval and Instrument Operation [PDF]

, 2010
The Earth Explorer Atmospheric Dynamics Mission (ADM-Aeolus) of ESA will be the first-ever satellite to provide global observations of wind profiles from space.
Vieitez, M. O., Stoffelen, A., Le Rille, O., Kloe, J., de Kloe, J., Vieitez, M.O., Ubachs, W., van de Water, W., Witschas, B., Ubachs, W.M.G.; id_orcid, Rille, O., Houchi, K., Körnich, H., Straume, A.-G., Schyberg, H., Marseille , G. J., Straume, A.G., Reitebuch, O., Marseille, G.J.   +18 more
core