Results 121 to 130 of about 446,660 (328)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Development of ultralow noise motors by using windings as a sensor (Noise reduction of motors by realizing an eccentricity of under one micrometer)

Nihon Kikai Gakkai ronbunshu, 2018
Motors are used in many appliances, and noise reduction is strongly demanded. One of the main causes of noise is electromagnetic excitation force and it is well known that the excitation force is increased by the eccentricity of the rotor to the stator ...
Yoshio YOSHIKUWA, Haruyuki KOMETANI, Yoshinori MIYAMOTO, Masaki KAMEYAMA, Manabu DEGUCHI, Toshihiko MIZUTANI   +5 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

An armature winding parameter calculation technique for an automotive compositely excited generator

Electrical engineering & Electromechanics, 2014
The paper deals with problems of determining armature reaction inductance in the longitudinal and transverse axes of an induction automotive generator.
A.N. Petrenko
doaj  

Moduli Stabilization with Long Winding Strings

, 2006
Stabilizing all of the modulus fields coming from compactifications of string theory on internal manifolds is one of the outstanding challenges for string cosmology.
A. Kaya, A. Saltman, B.S. Acharya, E. Dudas, E. Silverstein, J. Kripfganz, J. Polchinski, J.F.G. Cascales, K. Dasgupta, L. Kofman, M. Green, R. Easther, R. Kallosh, Robert Brandenberger, S. Kachru, S. Kachru, S. Kachru, S. Watson, S. Watson, S.H.S. Alexander, Scott Watson, T. Battefeld, T. Battefeld, T. Biswas, T. Boehm, T. Mohaupt, Y.-K.E. Cheung, Yeuk-Kwan E Cheung   +27 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

High-Frequency Model of the Toroidal Powder Core and Winding of a Litz Wire

Energies
A high-frequency model of the toroidal powder core inductor with litz wire winding is presented. In the analyzed model, the power losses that occurred in both the winding and the magnetic core were taken into account.
Marcin Pawlak, Urszula Pawlak
doaj   +1 more source

Winding Strings in AdS_3

, 2006
Correlation functions of one unit spectral flowed states in string theory on AdS_3 are considered. We present the modified Knizhnik-Zamolodchikov and null vector equations to be satisfied by amplitudes containing states in winding sector one and study ...
A. Zamolodchikov, A.B. Zamolodchikov, Carmen Núnez, D.M. Hofman, Estanislao Herscovich, G. Giribet, Pablo Minces, S. Ribault, T. Fukuda   +8 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source