Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
, 2013 We experimentally investigate the phase winding dynamics of a harmonically trapped two-component BEC subject to microwave induced Rabi oscillations between two pseudospin components.
Chang, J. J. +4 more
core +1 more source
Influence Analysis of Structural Parameters on the Performance of 120° Phase Belts Toroidal Winding Solid Rotor Induction Motor [PDF]
, 2020 Shaofeng Chen +5 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Development of a renewable hybrid power plant with extended utilization of pumped storage unit equipment [PDF]
, 2019 The scheme of a renewable hybrid power plant with the extended use of the installed equipment of the pumped storage unit for the conversion of the photovoltaic and wind generators direct current to the alternating one is proposed.
Chervonenko, I. +2 more
core
Reduction of Electromagnetic Force in AC Distributed Winding of Fault Current Limiter under Short-Circuit Condition [PDF]
, 2015 Asef Ghabeli +3 more
openalex +1 more source
VECTOR CONTROL OF AN ELECTRIC DRIVE BASED ON A THYRATRON MOTOR WITH DISCRETE WINDING COMMUTATION
, 2022 Сергей Григорьевич Воронин +3 more
openalex +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Solid-State Transformers for Interfacing Solar Panels to the Power Grid: An Optimum Design Methodology of a High Frequency Transformer for dc-dc Converter Applications [PDF]
, 2016 Nowadays the use of power electronic interfaces to integrate distributed generation with the power grid is becoming relevant due to the increased penetration of renewable energy sources like solar, and the continued ...
George, Kenny
core +2 more sources