Results 51 to 60 of about 1,001,880 (302)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Solving the problems of daylighting and tradition continuity in a reconstructed vernacular building
Journal of Civil Engineering and Management, 2013 Seeking for saving traditional forms, sizes, proportions and other features of vernacular architecture and satisfying norms for a contemporary building sometimes is not an easy task.
Eglė Šiožinytė +1 more
doaj +1 more source
A Windows Server 2003 hálózati megoldásai [PDF]
, 2008 Windows hálózati megoldások és biztonsági ...
Bíró, Zoltán
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Zhejiang Daxue xuebao. Lixue ban, 2012 讨论了Linux程序在Windows上移植的通用方法，通过将Linux下Linpop即时通讯软件移植到Windows上的实际项目，阐述在Windows下如何通过MinGW+MSYS等工具以及GTK+开发包，将Linux下基于GTK +的C程序移植到Windows上.同时对移植中可能会产生的网络通信、多线程等问题进行了分析和解决，使最终移植后的程序能够稳定地运行于Windows上，并且使最终处理后的程序源代码可以同时在Linux和Windows下跨平台编译并能够稳定运行.
KONGMei-yun(孔美云) +2 more
doaj +1 more source
Design of Wideband Absorber Based on Dual-Resistor-Loaded Metallic Strips
International Journal of Antennas and Propagation, 2020 A method for designing a dual-polarized wideband absorber with low profile by using dual-resistor-loaded metallic strips is proposed in this paper. Each unit cell consists of a resistive sheet with dual-resistor-loaded metallic strips and an underlying ...
Mingxi Zhang +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Using portable monitoring for heterogeneous clusters on Windows and Linux operating systems
Journal of Computer Science and Technology, 2003 This paper describes the advances obtained with the XPVM-W95 2.0, a novel monitoring tool for parallel applications that employ PVM-W95 (PVM for Windows) as well as PVM for Linux.
Daniel Kikuti +2 more
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source