Results 131 to 140 of about 1,598,590 (349)
Geosciences, 2019 Climate reanalyses provide key information to calibrate proxy records in regions with scarce direct observations. The climate reanalysis used to perform a proxy calibration should accurately reproduce the local climate variability.
Dieter Tetzner +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Arcadian Winds, November 28, 1989 [PDF]
, 1989 This is the concert program of Arcadian Winds performance on Tuesday, November 28, 1989 at 8:30 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts. Works performed were Wind Quintet by Paul Brust, Operation Flabby
School of Music, Boston University
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Observations of vertical winds and the origin of thermospheric gravity waves launched by auroral substorms and westward travelling surges [PDF]
Several sequences of observations of strong vertical winds in the upper thermosphere are discussed, in conjunction with models of the generation of such winds. In the auroral oval, the strongest upward winds are observed in or close to regions of intense
Rees, D.
core +1 more source
Arcadian Winds, January 18, 1991 [PDF]
, 1991 This is the concert program of the Arcadian Winds performance on Friday, January 18, 1991 at 8:30 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core
Stellar magnetism, winds and their effects on planetary environments
, 2016 Here, I review some recent works on magnetism of cool, main-sequence stars, their winds and potential impact on surrounding exoplanets. The winds of these stars are very tenuous and persist during their lifetime.
Vidotto, A. A.
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source