Results 111 to 120 of about 1,146,031 (297)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Observations of atmospheric gravity waves using airglow all-sky CCD imager at Cachoeira Paulista, Brazil (23° S, 45° W) [PDF]

Geofísica Internacional, 2004
An all-sky CCD imager for OH, O2 and OI (557.7 nm) airglow was operated at Cachoeira Paulista (CP), Brazil, (23° S, 45° W), from October 1998 to September 1999, with Utah State University.
M. J. Taylor, D. Gobbi, P. P. Batista, H. Takahashi, A. F. Medeiros   +4 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Observational evidence of the relationship between the tropical tropopause and tropical easterly jet streams over the Indian monsoon region

Atmospheric Science Letters
This paper presents the first quantitative relationship between the cold point tropopause (CPT) and tropical easterly jet (TEJ) using radiosonde observations over Gadanki (13.45° N, 79.2° E) during the Indian summer monsoon season 2006–2014.
Sanjay Kumar Mehta
doaj   +1 more source

A Validation of ERA5 Reanalysis Data in the Southern Antarctic Peninsula—Ellsworth Land Region, and Its Implications for Ice Core Studies

Geosciences, 2019
Climate reanalyses provide key information to calibrate proxy records in regions with scarce direct observations. The climate reanalysis used to perform a proxy calibration should accurately reproduce the local climate variability.
Dieter Tetzner, Elizabeth Thomas, Claire Allen   +2 more
doaj   +1 more source

Symphonic Winds Tour (1981)

, 1981
Twelfth Annual Concert Tour [to North Dakota and Montana]. Featuring the Symphonic Winds Repertory.
Bismarck Junior College Symphonic Winds
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Dissipation Regime of Turbulence on Mars Observed With Microphone Data From the Mars 2020 Perseverance Rover

Geophysical Research Letters
Turbulent winds are a regular occurrence in planetary boundary layers. Turbulence affects mixing, energy fluxes and forcing on the surface environment.
Alexander E. Stott, Naomi Murdoch, Martin Gillier, German Martinez, Tanguy Bertrand, Ralph Lorenz, Claire Newman, Ricardo Hueso, Manuel de la Torre Juárez, Donald Banfield, Sylvestre Maurice, Baptiste Chide, Jose Antonio Rodriguez Manfredi, David Mimoun   +13 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Western Winds, February 14, 1999

, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, February 14, 1999, 8:00 p.m., the 277th concert of the School of Music's 1998-1999 season.Western Winds (variously), Robert L.
Western Winds
core   +1 more source