Results 111 to 120 of about 600 (218)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

What climate adaptation can learn from evolutionary adaptation

Conservation Biology, EarlyView.
Abstract Evolutionary and climate adaptation both describe how complex systems respond to environmental change, either via natural selection or deliberate human choices. Although adaptation in both contexts is expected to produce favorable outcomes, it can also result in maladaptation—ineffective, unintended, or harmful outcomes. As an emerging area of
Amy Waananen, Katherine T. Charton, Jessica J. Hellmann   +2 more
wiley   +1 more source

Optimizing biodiversity offsetting for habitat succession and colonization dynamics

Conservation Biology, EarlyView.
Abstract Biodiversity offsetting aims to compensate for ecological losses from development through conservation and restoration. However, its long‐term outcomes under repeated impact–offset cycles remain uncertain. Using a conceptual forest succession model, we evaluated how offset outcomes are affected by interactions among compensation scale ...
Konstans Wells, Luca Börger, Miguel Lurgi, Kevin Watts, James M. Bullock   +4 more
wiley   +1 more source

Multiclass convolutional neural network vs. 96 dermatologists in skin lesion diagnosis, an international study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Artificial intelligence was shown to improve diagnostic accuracy for skin cancer detection. While most clinically approved models provide binary “benign/malignant” classifications, multiclass predictions may offer greater clinical utility.
Katharina Susanne Kommoss, Julia Katharina Winkler, Anastasia Sophie Vollmer, Christine Mueller‐Christmann, Ferdinand Toberer, Wilhelm Stolz, Teresa Kraenke, Rainer Hofmann‐Wellenhof, Andreas Blum, Alexander Enk, Albert Rosenberger, Holger Andreas Haenssle   +11 more
wiley   +1 more source

An assessment of winkler model for simulation of shallow foundation uplift

, 2008
Temel kalkması, aşırı yük eksantrikliği nedeniyle yüzeysel bir temelin zeminle temasının kısmen kaybolmasıdır. Temel kalkması narin yapıların ve çerçevelerin sismik davranışını belirgin şekilde değiştirebilir. Literatürde, deprem yüklerinin düşünüldüğü yapısal analizlerde temel kalkmasının benzetimini gerçekleştirebilmek için, çok sayıda temel desteği ...
openaire   +2 more sources

Effect of soil-structure interaction and flexibility of base on reduction of shear base by BNWF method [PDF]

مهندسی و مدیریت ساخت
The effects of Soil-Structure Interaction and base flexibility on reduction of base shear has been investigated using BNWF method in this article.
Iman Hakamian
doaj  

Age‐related dermatoscopic features of excised melanomas versus nevi in 832 high risk patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Melanocytic nevi show distinct age‐related dermoscopic patterns. However, data on age‐related patterns of melanomas are lacking. This study aimed to identify age‐related static and dynamic dermoscopic patterns of melanomas. Patients and methods Explorative cross‐sectional cohort study between October 1996 and May 2012,
Jana Burghaus‐Zhang, Julia Katharina Winkler, Katharina Susanne Kommoss, Anastasia Sophie Vollmer, Alexander Enk, Timo Buhl, Holger Andreas Haenssle   +6 more
wiley   +1 more source

Comparative Study on Dynamic Behaviour of Thick Beams on Foundation: Winkler, Pasternak and Kerr Foundation

Journal of Materials and Engineering Structures
A comparative study amongst different types of elastic foundation of a bi-directionally graded beam mounted on elastic foundation is carried out. A single parameter Winkler, two parameters Pasternak and three parameters Kerr foundation are considered as ...
Hareram LOHAR, Anirban MITRA
doaj  

Robustness of a neural network approved for skin cancer diagnosis against variations in sequential images

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Convolutional neural networks (CNN) for skin cancer classification have shown results comparable to dermatologists but are vulnerable to minor image transformations. We investigated the robustness of a MDR class‐IIa certified CNN when classifying sequential images of identical lesions.
Alicia Zimmermann, Julia K. Winkler, Katharina Kommoss, Anastasia Vollmer, Ferdinand Toberer, Alexander Enk, Albert Rosenberger, Holger A. Haenssle   +7 more
wiley   +1 more source

Access to Credit and Employment Liquidation. Firm‐Level Evidence From Eastern and Central Europe (2001–2007)

Economics of Transition and Institutional Change, EarlyView.
ABSTRACT This article investigates the changes in the structure of employment in Central and Eastern European firms between 2001 and 2007, before the Global Financial Crisis and following the reforms in the labour and credit markets in these economies.
Elisabetta Magnani
wiley   +1 more source