Results 121 to 130 of about 12,439 (266)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

Larval character evolution in Holometabola (Insecta)

open access: yesCladistics, EarlyView.
Abstract Larvae, a novel type of immature stage, are a crucial innovation of the Holometabola. Larval features therefore provide key evidence for reconstructing evolutionary transformations in this megadiverse group. Here we present the first formal reconstruction of larval character evolution, using maximum parsimony and Bayesian ancestral‐state ...
Rolf Georg Beutel, Jakub Goczał, Di Li
wiley   +1 more source

What climate adaptation can learn from evolutionary adaptation

open access: yesConservation Biology, EarlyView.
Abstract Evolutionary and climate adaptation both describe how complex systems respond to environmental change, either via natural selection or deliberate human choices. Although adaptation in both contexts is expected to produce favorable outcomes, it can also result in maladaptation—ineffective, unintended, or harmful outcomes. As an emerging area of
Amy Waananen   +2 more
wiley   +1 more source

Optimizing biodiversity offsetting for habitat succession and colonization dynamics

open access: yesConservation Biology, EarlyView.
Abstract Biodiversity offsetting aims to compensate for ecological losses from development through conservation and restoration. However, its long‐term outcomes under repeated impact–offset cycles remain uncertain. Using a conceptual forest succession model, we evaluated how offset outcomes are affected by interactions among compensation scale ...
Konstans Wells   +4 more
wiley   +1 more source

Integrating Indigenous knowledge and modern statistical approaches to model wildlife density based on animal track counts

open access: yesConservation Biology, EarlyView.
Abstract In multiuse areas outside formal protection, sustaining both wildlife and people is critical to wildlife conservation and coexistence efforts. Botswana's Kalahari hosts one of sub‐Saharan Africa’s largest unprotected areas supporting free‐ranging wildlife.
Marie‐Charlotte Gielen   +7 more
wiley   +1 more source

Multiclass convolutional neural network vs. 96 dermatologists in skin lesion diagnosis, an international study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Artificial intelligence was shown to improve diagnostic accuracy for skin cancer detection. While most clinically approved models provide binary “benign/malignant” classifications, multiclass predictions may offer greater clinical utility.
Katharina Susanne Kommoss   +11 more
wiley   +1 more source

Immediate intraoperative detrusor muscle status at primary transurethral resection of bladder tumour: a prospective, blinded, paired cohort, feasibility study using fluorescence confocal microscopy (IB1-LaserComplete study). [PDF]

open access: yesBJU Int
Connor MJ   +20 more
europepmc   +1 more source

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