Results 21 to 30 of about 281,017 (295)

Spatially-adaptive dynamic dictionary learning for fine-grained remote sensing image segmentation

Scientific Reports
Dynamic dictionary learning provides explicit class-level semantic prototypes for remote sensing image segmentation. However, most existing methods generate one global dictionary for the whole image through global feature aggregation, which overlooks the
Yan Zhang, Zifei Luo, Bo Yang, Zhangkai Chen, Yunkun Zou   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Wit and wisdom [PDF]

Nature, 2005
From pioneering xerographer to innovative teacher, Georg Christoph Lichtenberg was a physicist with many skills, but perhaps most remembered will be his acerbic aphorisms.
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Mitochondrial mutation status, symptom prevalence, and neuroimaging characteristics in MELAS: a systematic review and meta analysis

Orphanet Journal of Rare Diseases
Background Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a rare mitochondrial disorder characterized by a wide range of systemic manifestations.
Yanyan Li, Siying Han, Daiyun Huang, Jiayi Chen, Siying Qu, Jinxin Gu, Zhuoyan Xu, Lei Fu, Xiaoyu Tang, Yixue Qiao   +9 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Bioengineering of extracellular vesicles with scaffold proteins for drug delivery

Journal of Nanobiotechnology
Extracellular vesicles (EVs) play a crucial role in intercellular communication by transmitting information and participate in various physiological and pathological processes, including cancer, neurodegenerative diseases, and cardiovascular diseases ...
Chaofan Zhang, Yue Wu, Yuezhou Wang, Cunbo Yao, Mengting Ma, Jiacong Li, Qiang Wu   +6 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Fine classification of rice fields in high-resolution remote sensing images

Scientific Reports
Fine-grained management of rice fields can enhance the yield and quality of rice crops. Challenges in achieving fine classification include interference from similar vegetation, the irregularity of natural field shapes, and complex scale variations. This
Lingyuan Zhao, Zifei Luo, Kuang Zhou, Bo Yang, Yan Zhang   +4 more
doaj   +1 more source

Multi-View and Multi-Language Description Generation for Cross-Department Medical Diagnosis Processes

IEEE Access, 2018
Cross-department medical diagnosis processes typically involve several coordination patterns among different departments. In addition, medical task participants may come from different countries and use different languages, which makes diagnosis ...
Guiyuan Yuan, Qingtian Zeng, Weijian Ni, Cong Liu, Chao Li, Hua Duan   +5 more
doaj   +1 more source