Results 31 to 40 of about 196,697 (301)

Association between housework frequency and cognitive impairment among Chinese older adults: a prospective cohort study based on CLHLS

open access: yesBMC Public Health
Background Housework is a crucial aspect of instrumental activities of daily living (IADL), essential for maintaining the independence of older adults.
Zhenni Wang   +3 more
doaj   +1 more source

Comparing Bayesian-Based Reconstruction Strategies in Topology-Based Pathway Enrichment Analysis

open access: yesBiomolecules, 2022
The development of high-throughput omics technologies has enabled the quantification of vast amounts of genes and gene products in the whole genome. Pathway enrichment analysis (PEA) provides an intuitive solution for extracting biological insights from ...
Yajunzi Wang   +8 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Arthur Godfrey's Talent Scout Show in New York City [PDF]

open access: yes, 1957
Scrapbook by Diane Wisdom containing letters, telegrams, newspaper clippings, tickets, and other ephemera from the events of May 16, 1957 when Diane Wisdom is accepted into Arthur Godfrey's Talent Scout Show to fan mail postmarked August 02, 1957 after ...
Wisdom, Diane
core  

Effect of Different Adjuvants on the Immunogenicity of a Recombinant Herpes Zoster Vaccine in Mice, Rats and Non-Human Primates

open access: yesVaccines
Background: Varicella zoster virus (VZV) is a globally circulating pathogen that usually infects children and establishes a latent state in host nerve cells.
Xiaoyang Liu   +9 more
doaj   +1 more source

Investigating the Marginal and Herd Effects of COVID-19 Vaccination for Reducing Case Fatality Rate: Evidence from the United States between March 2021 to January 2022

open access: yesVaccines, 2023
Vaccination campaigns have been rolled out in most countries to increase vaccination coverage and protect against case mortality during the ongoing pandemic.
Tenglong Li   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The Possibility of the Rational Knowledge of God in the Teachings of Hakīm Sabzawārī [PDF]

open access: yesحکمت معاصر, 2017
The question of ‘knowability of God’ is not a major topic in the works of traditional Muslim philosophers, as if taken for granted. Despite his critical view of ‘those who divest God of His Attributes’ (mu’attila) - hence, actually divest the concept of ...
Mohammad Hadi Tavakoli, Azam Ghasemi
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

[Diane Wisdom at Hassell With Wisdom Event] [PDF]

open access: yes, 1968
Image of Diane ...
Unknown
core  

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