Results 51 to 60 of about 254,224 (295)

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

The Colonial Legacy of Power, Profit, and Prejudice in Global Health Governance

open access: yesModern Africa
This article examines how colonial legacies continue to structure global health financing and governance, perpetuating systemic inequities between the Global North and South, particularly African countries.
Lyla Latif, Harrison Otieno
doaj   +1 more source

Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages

open access: yesCanine Medicine and Genetics, 2020
Background Discrete breed ideals are not restricted to delimiting dog breeds from another, but also are key drivers of subpopulation differentiation. As genetic differentiation due to population fragmentation results in increased rates of inbreeding and ...
Sara Lampi   +3 more
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Unconventional Wisdom

open access: yesIEEE Security & Privacy Magazine, 2006
We are told that passwords are evil. We are told to change our passwords frequently, and never, never to write them down. We are even told that if you work for most U.S. corporations, frequent password changes are required by law. How much of this is true, and how much is simply mythology?
openaire   +2 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Spatio-temporal modelling of extreme low birth rates in U.S. counties

open access: yesBMC Public Health
The continuous declining rate of birth may cause severe worldwide problems, including population ageing and demographic imbalance. This paper aims to identify the geographic disparities and potential influential factors of the extreme downward excess of ...
Kai Wang   +4 more
doaj   +1 more source

Universities: from knowledge to wisdom [PDF]

open access: yes, 2010
We need a revolution in academic inquiry so that problems of living are put at the heart of the academic enterprise, and the basic aim becomes to seek and promote wisdom.
Maxwell, Nicholas, Maxwell, N
core  

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