Results 221 to 230 of about 427,006 (340)

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal‐Weight Rats, Prevented by Perinatal Leptin Intake

open access: yesMolecular Nutrition &Food Research, EarlyView.
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano   +3 more
wiley   +1 more source

Sex‐Specific Lasting Metabolome Effects of Adverse Gestational Conditions and Prevention by Myo‐Inositol Supplementation During Suckling

open access: yesMolecular Nutrition &Food Research, EarlyView.
This graphical abstract illustrates the effects of myo‐inositol supplementation during suckling in reducing long‐term metabolic impacts from mild gestational calorie restriction (GCR). Using a metabolomics approach, 164 metabolites were identified, with greater metabolic alterations in males.
Rocío A. Martín‐Chamorro   +6 more
wiley   +1 more source

Benefits of Nutrients and Phytonutrients in Nuts and Legumes on Platelet Aggregation Through DNA Methylation

open access: yesMolecular Nutrition &Food Research, EarlyView.
Nuts and legumes contain both nutrients and bioactive compounds supporting cardiovascular health related to influencing DNA methylation. These foods are related to reducing oxidative stress, supplying methyl donors, and modulating genes involved in platelet function, such as PEAR1 and mitochondrial genes, in association with helping reduce inflammation
Siwaphorn Chaimati   +2 more
wiley   +1 more source

Integrating Nanotechnology With 3D Printing for Drug Delivery: Bone Regeneration and Beyond

open access: yesNano Select, EarlyView.
What happens when nanotechnology meets 3D printing? This review explores how their fusion transforms drug delivery and bone regeneration, creating smarter, more adaptable therapies. From nanomaterials to futuristic fabrication methods, the article maps innovations that could redefine personalized medicine and hints at the challenges researchers must ...
Felipe Sousa Siqueira   +2 more
wiley   +1 more source

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