Results 1 to 10 of about 2,999 (92)

Dietary phytosterols and phytostanols decrease cholesterol levels but increase blood pressure in WKY inbred rats in the absence of salt-loading [PDF]

open access: yesNutrition & Metabolism, 2010
Background There are safety concerns regarding widespread consumption of phytosterol and phytostanol supplemented food products. The aim of this study was to determine, in the absence of excess dietary salt, the individual effects of excess accumulation ...
Ratnayake Walisundera MN   +6 more
doaj   +3 more sources

Graft arteriosclerosis develops spontaneously after heart transplant in “inbred” wistar-kyoto (WKY) and spontaneously hypertensive (SHR) rats

open access: yesJournal of the American College of Cardiology, 1990
Smith, Vivienne-E.   +2 more
exaly   +2 more sources

WKY/Ztm -ter : a new rat inbred strain on the WKY/Ztm genetic background with congenital teratomas [PDF]

open access: yesLaboratory Animals, 2004
We describe a new rat model for teratomas (WKY/Ztm- ter) which arose through a spontaneous mutation in the inbred WKY/Ztm rat strain. When the tumours of the gonads became clinically apparent, affected males were 14 to 224 days of age, whereas the females only developed tumours between days 21 and 63. Tumour incidence is not gender-dependent.
B, Länger   +5 more
openaire   +2 more sources

Influence of dietary phytosterols and phytostanols on diastolic blood pressure and the expression of blood pressure regulatory genes in SHRSP and WKY inbred rats [PDF]

open access: yesBritish Journal of Nutrition, 2008
The aim of the present study was to determine the impact of increased consumption of phytosterols or phytostanols on blood pressure and renal blood pressure regulatory gene expression in stroke-prone spontaneously hypertensive (SHRSP) and normotensive Wistar–Kyoto (WKY) inbred rats. SHRSP and WKY inbred rats (10/group) were fed a control diet or a diet
Qixuan, Chen   +5 more
openaire   +2 more sources

Partial Predictability in Avoidance Acquisition and Expression of Wistar-Kyoto and Sprague-Dawley Rats: Implications for Anxiety Vulnerability in Uncertain Situations

open access: yesFrontiers in Psychiatry, 2020
Individual differences or vulnerabilities must exist which bias some individuals toward psychopathology while others remain resilient in the face of trauma.
Daniel Paul Miller   +5 more
doaj   +1 more source

Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity

open access: yesScientific Reports, 2021
The WMI and WLI inbred rats were generated from the stress-prone, and not yet fully inbred, Wistar Kyoto (WKY) strain. These were selected using bi-directional selection for immobility in the forced swim test and were then sib-mated for over 38 ...
Tristan V. de Jong   +6 more
doaj   +1 more source

Bone healing of mandibular critical-size defects in spontaneously hypertensive rats

open access: yesBrazilian Oral Research, 2013
Few articles have shown changes in bone metabolism caused by hypertension. The objective of this study was to investigate the relationship between hypertension and bone healing.
Veronica Kei Len Chin   +2 more
doaj   +1 more source

Avoidance Expression in Rats as a Function of Signal-Shock Interval: Strain and Sex Differences

open access: yesFrontiers in Behavioral Neuroscience, 2015
Inbred Wistar Kyoto (WKY) rats express inhibited temperament, increased sensitivity to stress, and exaggerated expressions of avoidance. A long-standing observation for lever press escape/avoidance learning in rats is the duration of the warning signal (
Richard J Servatius   +14 more
doaj   +1 more source

Avoidance as expectancy in rats: Sex and strain differences in acquisition

open access: yesFrontiers in Behavioral Neuroscience, 2014
Avoidance is a core feature of anxiety disorders and factors which increase avoidance expression or its resistance represent a source of vulnerability for anxiety disorders. Outbred female Sprague Dawley (SD) rats and inbred male and female Wistar-Kyoto (
Pelin eAvcu   +19 more
doaj   +1 more source

Dopaminergic Modulation of Goal-Directed Behavior in a Rodent Model of Attention-Deficit/Hyperactivity Disorder

open access: yesFrontiers in Integrative Neuroscience, 2018
Aside from its clinical symptoms of inattention, impulsivity and hyperactivity, patients with Attention/Deficit-Hyperactivity Disorder (ADHD) display reward and motivational impairments. These impairments may reflect a deficit in action control, that is,
Joman Y. Natsheh   +4 more
doaj   +1 more source

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