Results 21 to 30 of about 717,881 (139)

Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains [PDF]

, 2009
Background Cognitive function might be affected by the subjects' emotional reactivity. We assessed whether behavior in different tests of emotional reactivity is correlated with performance in aversively motivated learning tasks, using four strains of ...
Korte S Mechiel, Schuurman Teun, Korte, S.M., Sub BasicPharmacology&Psychopharmacology, Staay, F.J., van der, van Reenen, C.G., van der Staay F Josef, van der Staay, F.J., Cornelis G van Reenen, Schuurman, T., Reenen, C.G., van, Dep Gezondheidszorg Landbouwhuisdieren, F Josef van der Staay, van Reenen Cornelis G, Emotion and Cognition, S Mechiel Korte, Dierexperimenteel, Teun Schuurman   +17 more
core   +2 more sources

Dorsal cerebral collaterals of stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar Kyoto rats (WKY) [PDF]

, 1987
Earlier studies established that stroke-prone spontaneously hypertensive rats (SHRSP) invariably infarct after middle cerebral artery (MCA) occlusion. Normotensive rats are usually protected from infarction after the occlusion.
Coyle, Peter
core   +1 more source

Inter-strain differences of serotonergic inhibitory pain control in inbred mice [PDF]

, 2010
Background: Descending inhibitory pain control contributes to the endogenous defense against chronic pain and involves noradrenergic and serotonergic systems.
Albuquerque Boris, Irmgard Tegeder, Tegeder Irmgard, Laura Popp, Wijnvoord, Nina, Myrczek, Thekla, Tegeder, Irmgard, Wijnvoord Nina, Popp, Laura, Annett Häussler, Häussler, Annett, Nina Wijnvoord, Myrczek Thekla, Häussler Annett, Popp Laura, Boris Albuquerque, Albuquerque, Boris, Thekla Myrczek   +17 more
core   +1 more source

New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein

Disease Models & Mechanisms, 2016
The Wistar Kyoto (WKY) rat and the spontaneously hypertensive (SHR) rat inbred strains are well-established models for human crescentic glomerulonephritis (CRGN) and metabolic syndrome, respectively.
Ana Isabel Garcia Diaz, Ben Moyon, Philip M. Coan, Neza Alfazema, Lara Venda, Kevin Woollard, Tim Aitman   +6 more
doaj   +1 more source

Nociception and conditioned fear in rats: strains matter.

PLoS ONE, 2013
When using rats in pain research, strain-related differences in outcomes of tests for pain and nociception are acknowledged. However, very little is known about the specific characteristics of these strain differences. In this study four phylogenetically
Manon W H Schaap, Hugo van Oostrom, Arie Doornenbal, José van 't Klooster, Annemarie M Baars, Saskia S Arndt, Ludo J Hellebrekers   +6 more
doaj   +1 more source

Effects of early life trauma are dependent on genetic predisposition: a rat study

Behavioral and Brain Functions, 2011
Background Trauma experienced early in life increases the risk of developing a number of psychological and/or behavioural disorders. It is unclear, however, how genetic predisposition to a behavioural disorder, such as attention-deficit/hyperactivity ...
Russell Vivienne A, Howells Fleur M, Sterley Toni-Lee   +2 more
doaj   +1 more source

Strain differences in baroceptor reflex in adult Wistar Kyoto rats

Clinics, 2010
OBJECTIVES: A subset of normotensive Sprague-Dawley rats show lower baroreflex sensitivity; however, no previous study investigated whether there are differences in baroreflex sensitivity within this subset.
Vitor E. Valenti, Luiz Carlos de Abreu, Caio Imaizumi, Márcio Petenusso, Celso Ferreira   +4 more
doaj   +1 more source

Influence of arterial hypertension on colonic healing in rats Influência da hipertensão arterial na cicatrização colônica em ratos

Acta Cirúrgica Brasileira, 2012
PURPOSE: Evaluation of colonic healing in spontaneously hypertensive rats. METHODS: Fifty male, young and inbred rats were used. Twenty-five Wistar Kyoto rats (WKY) as control and twenty-five spontaneously hypertensive rats (SHR) as an experimental group.
Gilberto Luiz Ortolan, Maria de Lourdes Pessole Biondo-Simões, Giovani Marino Fávero, Daniel Fernandes, Mário Rodrigues Montemór Netto, Luiz Renato Olchanheski Jr   +5 more
doaj   +1 more source

Genetic Model to Study the Co-Morbid Phenotypes of Increased Alcohol Intake and Prior Stress-Induced Enhanced Fear Memory

Frontiers in Genetics, 2018
Posttraumatic Stress Disorder (PTSD) is a complex illness, frequently co-morbid with depression, caused by both genetics, and the environment. Alcohol Use Disorder (AUD), which also co-occurs with depression, is often co-morbid with PTSD.
Patrick Henry Lim, Guang Shi, Tengfei Wang, Sophia T. Jenz, Megan K. Mulligan, Eva E. Redei, Hao Chen   +6 more
doaj   +1 more source

Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat

Disease Models & Mechanisms, 2017
We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified
Philip M. Coan, Oliver Hummel, Ana Garcia Diaz, Marjorie Barrier, Neza Alfazema, Penny J. Norsworthy, Michal Pravenec, Enrico Petretto, Norbert Hübner, Timothy J. Aitman   +9 more
doaj   +1 more source