A comparison of the results from intra-pleural and intra-peritoneal studies with those from inhalation and intratracheal tests for the assessment of pulmonary responses to inhalable dusts and fibres. [PDF]
The aim of this paper is to compare results from inhalation studies with those from intraperitoneal and intrapleural tests, where available, for a number of fibrous and particulate test materials.
Bevan, Ruth +2 more
core +2 more sources
Pathologic Diagnosis of a Pituicytoma in a Han-Wistar Rat
A case of pituicytoma was observed in a Han-Wistar rat from the control group of a 2-year carcinogenicity study. No obvious abnormality were found in clinical observation and necropsy.
HOU Minbo +7 more
doaj +1 more source
Effect of Wheat/Cassava Composite Bread on Liver Architecture of Wistar Rat
This study reports the effect of different levels of wheat/cassava composite flour on liver architecture of wistar rat. The cassava variety- TMS 98/419 and Twenty (20) male wistar rats were used for the study.
M.O. Odo +3 more
doaj +1 more source
Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M. +3 more
core +1 more source
The mandibular gland in rodents presents a distinct type of ducts, granular, which are not encountered in other mammal species. Our aim was to conduct a stereological study in order to compare the number of striated and granular ducts on the section ...
Flavia Ruxanda +4 more
doaj +1 more source
Anesthesia protocol for ear surgery in Wistar rats (animal research)
Objective To formulate an anesthesia protocol for safe and satisfactory anesthesia for ear surgery in rats. Methods The rats were anesthetized with xylazine (10 mg/kg body weight) and ketamine at doses of 80, 50, 40, and 30 mg/kg body weight or with ...
Abhijeet Bhatia +3 more
doaj +1 more source
Background To test whether epithelial sodium channel (ENaC) genes' variants contribute to salt sensitive hypertension in Dahl rats, we screened ENaC α, β, and γ genes entire coding regions, intron-exon junctions, and the 3' and 5' flanking regions in ...
Leenen Frans HH +2 more
doaj +1 more source
Discriminating Different Classes of Toxicants by Transcript Profiling [PDF]
Male rats were treated with various model compounds or the appropriate vehicle controls. Most substances were either well-known hepatotoxicants or showed hepatotoxicity during preclinical testing.
Albertini, Silvio +6 more
core +2 more sources
GAMBARAN HISTOPATOLOGI PARU TIKUS WISTAR SETELAH DIBERI PAPARAN ASAP ROKOK
: Cigarette smoke is the main cause of lung obstruction. One of the obstructions in real that is caused by cigarette smoke is oxidative stress. Oxidative stress trigger inflammation response occur and lung obstruction.
Novera Herdiani +1 more
doaj +1 more source
Abnormal hippocampal melatoninergic system: a potential link between absence epilepsy and depression-like behavior in WAG/Rij rats? [PDF]
Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like ...
Battaglia, Giuseppe +8 more
core +1 more source

