Results 101 to 110 of about 1,615,506 (361)

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira   +12 more
wiley   +1 more source

Effect of Wheat/Cassava Composite Bread on Liver Architecture of Wistar Rat

open access: yesJournal of Pure and Applied Microbiology, 2018
This study reports the effect of different levels of wheat/cassava composite flour on liver architecture of wistar rat. The cassava variety- TMS 98/419 and Twenty (20) male wistar rats were used for the study.
M.O. Odo   +3 more
doaj   +1 more source

Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats

open access: yesAdvances in Pharmacological Sciences, 2014
Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (
M. Aslam, Ali Akbar Sial
semanticscholar   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

Sevoflurane Induces Exaggerated and Persistent Cognitive Decline in a Type II Diabetic Rat Model by Aggregating Hippocampal Inflammation

open access: yesFrontiers in Pharmacology, 2017
Recent studies show that a moderate duration of sevoflurane, one of the most commonly used volatile anesthetics in clinical practice, does not induce cognitive impairment in animals under physiological conditions. However, the influence of sevoflurane on
Dongliang Li   +11 more
doaj   +1 more source

Wistar rats: a forgotten model of age-related hearing loss

open access: yesFrontiers in Aging Neuroscience, 2014
Age-related hearing loss (ARHL) is one of the most frequent sensory impairments in senescence and is a source of important socio-economic consequences.
J. Alvarado   +4 more
semanticscholar   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Effect of alcohol on the endocrine glands of pregnant wistar rats

open access: yesSahel Medical Journal, 2010
Background: An investigation was conducted to determine the effect of alcohol on some endocrine glands of pregnant Wistar rats. Methods: Thirty female Wistar rats divided into 2 groups of 15 each were used.
J E Onu   +3 more
doaj  

An algorithm for seizure detection in rodents

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky   +9 more
wiley   +1 more source

Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats

open access: yesPsychopharmacology, 2020
A. Kimbrough   +9 more
semanticscholar   +1 more source

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