Results 11 to 20 of about 364,482 (359)
Observations on Leukemia in Wistar and Wistar Furth Rats [PDF]
Abstract 1. Six-hundred and seventy-three Wistar and W/Fu rats were treated at the age of 4 months with whole body x-ray, orally administered 3MCA or a combination of these agents. All animals were followed until death and 87 per cent were autopsied. 2. Among 303 autopsied animals there were 403 benign and malignant tumors,
William C. Moloney+2 more
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Spontaneous Synovitis in Wistar Rats [PDF]
Spontaneous synovitis has been detected in the stifle joints of control Wistar rats in 4-wk and 2-yr toxicity studies, and a specific site was found to be predisposed to synovitis. The incidence of synovitis was 27.5% for males in the 4-wk study and 40.0% for males and 16.0% for females in the 2-yr study. The severity was not increased with aging.
Hisashi Anayama+4 more
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Ototoxicity of cypermethrin in Wistar rats
This study presents the effect of cypermethrin on the cochlear function in Wistar rats post-subchronic inhalation exposure. Worldwide several pesticides are described as causing health disorders. Cypermethrin is currently one of the most commonly used, however, little is known about its harmful effects, especially related to hearing. Human studies have
Eduarda Oliveira Cunha+4 more
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Spontaneous Cholangiofibrosis in a Wistar Rat [PDF]
In a 2-year carcinogenicity study, we identified a spontaneous cholangiofibrosis in a control male Wistar rat. This lesion has long been considered as a compound-related change, with no spontaneous cases reported in the Wistar rat. In addition to routine hematoxylin and eosin stains evaluation, we applied Masson’s trichrome staining, Alcian blue ...
Tao Chen+3 more
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Auricular chondritis in Wistar rats [PDF]
The macroscopic and microscopic features of auricular chondritis in Wistar rats are described. Histologic lesions are characterized by granulomatous inflammation, chondrolysis, and multinodular proliferative foci. The condition in Wistar rats is compared to auricular chondritis in other strains of rats.
N. J. Barsoum, B. J. McEwen
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Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases [PDF]
For studies requiring accurate conception-timing, reliable, efficient methods of detecting oestrus reduce time and costs, whilst improving welfare. Standard methods use vaginal cytology to stage cycle, and breeders are paired–up using approximately five ...
Agata K Stramek+18 more
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Stevia preferences in Wistar rats
The Stevia rebaudiana plant is likely to become a major source of high-potency sweetener for the growing natural-food market. S. rebaudiana is the source of a number of sweet diterpenoid glycosides, but the major sweet constituents are rebaudioside A and stevioside.
Núñez Martínez, Paula+2 more
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Early weaning can predispose the offspring to greater risk of developing chronic diseases in adulthood. It is believed that the consumption of functional foods is able to prevent these effects. The aim of this study is to evaluate the effects of maternal
Carolina Alves Procópio de Oliveira+4 more
doaj +1 more source
Abnormal hippocampal melatoninergic system: a potential link between absence epilepsy and depression-like behavior in WAG/Rij rats? [PDF]
Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like ...
Battaglia, Giuseppe+8 more
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Impulsivity in rodents with a genetic predisposition for excessive alcohol consumption is associated with a lack of a prospective strategy [PDF]
Increasing evidence supports the hypothesis that impulsive decision-making is a heritable risk factor for an alcohol use disorder (AUD). Clearly identifying a link between impulsivity and AUD risk, however, is complicated by the fact that both AUDs and ...
Janetsian-Fritz, Sarine S.+3 more
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