A low coefficient of variation in hepatic triglyceride concentration in an inbred rat strain
Lipids in Health and Disease, 2020 Background Inbred strains are characterized by less genetic variation, which suggests usefulness of inbred strains for evaluations of various parameters.
Tomoko Shimoda +8 more
doaj +1 more source
Ototoxicity of cypermethrin in Wistar rats
Brazilian Journal of Otorhinolaryngology, 2020 This study presents the effect of cypermethrin on the cochlear function in Wistar rats post-subchronic inhalation exposure. Worldwide several pesticides are described as causing health disorders. Cypermethrin is currently one of the most commonly used, however, little is known about its harmful effects, especially related to hearing. Human studies have
Eduarda Oliveira Cunha +4 more
openaire +4 more sources
Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats. [PDF]
, 2008 The development of type 2 diabetes is accompanied by decreased immune function and the mechanisms are unclear. We hypothesize that oxidative damage and mitochondrial dysfunction may play an important role in the immune dysfunction in diabetes.
Hao, Jiejie +8 more
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Histometric analysis of gingival hyperplasia in Wistar rats during nifedipine administration [PDF]
Vojnosanitetski Pregled, 2007 Background/Aim. The use of calcium channel blockers, especially nifedipine, causes gingival hyperplasia which leads to the destruction of the deeper periodontal tissues.
Brkić Zlata
doaj +1 more source
Impulsivity in rodents with a genetic predisposition for excessive alcohol consumption is associated with a lack of a prospective strategy [PDF]
, 2016 Increasing evidence supports the hypothesis that impulsive decision-making is a heritable risk factor for an alcohol use disorder (AUD). Clearly identifying a link between impulsivity and AUD risk, however, is complicated by the fact that both AUDs and ...
Janetsian-Fritz, Sarine S. +3 more
core +2 more sources
Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats
Pharmaceutics, 2022 Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development.
Christine M. Madla +8 more
doaj +1 more source
Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases [PDF]
, 2018 For studies requiring accurate conception-timing, reliable, efficient methods of detecting oestrus reduce time and costs, whilst improving welfare. Standard methods use vaginal cytology to stage cycle, and breeders are paired–up using approximately five ...
Agata K Stramek +18 more
core +1 more source
Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]
, 2005 In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Borght, Karin van der, +4 more
core +3 more sources
Spontaneous Cholangiofibrosis in a Wistar Rat [PDF]
Toxicologic Pathology, 2019 In a 2-year carcinogenicity study, we identified a spontaneous cholangiofibrosis in a control male Wistar rat. This lesion has long been considered as a compound-related change, with no spontaneous cases reported in the Wistar rat. In addition to routine hematoxylin and eosin stains evaluation, we applied Masson’s trichrome staining, Alcian blue ...
Tao Chen +3 more
openaire +2 more sources
EVALUATION OF THE EXTRACELLULAR MATRIX OF INJURED SUPRASPINATUS IN RATS [PDF]
Acta Ortopédica Brasileira, 2016 Objective: To evaluate the evolution of injuries of the supraspinatus muscle by immunohistochemistry (IHC) and anatomopathological analysis in animal model (Wistar rats).
Luiz Henrique Oliveira Almeida +5 more
doaj +1 more source